静脉注射前列腺素E和内毒素对雏鸡的一些影响。
Some effects of intravenous prostaglandin E, and endotoxin in young chickens.
作者信息
Artunkal A A, Marley E, Stephenson J D
出版信息
Br J Pharmacol. 1977 Sep;61(1):29-37. doi: 10.1111/j.1476-5381.1977.tb09736.x.
Abstract
1 The effects of intravenous prostaglandin E1 and endotoxin were studied in young chickens (11-17 days old). 2 At a thermoneutral ambient temperature (31 degrees C), intravenous prostaglandin E1, produced behavioural and electrocortical sleep, increased oxygen consumption and, after an initial fall, elevated body temperature. Below thermoneutrality (16 degrees C), the initial hypothermic effect was more marked and oxygen consumption was lowered. 3 The soporific actions of prostaglandin E1 were sufficient to counteract dexamphetamine-induced behavioural and electrocortical arousal and vocalization. 4 Intravenous injection of the O-somatic antigen of Shigella dysenteriae evoked, after a latent period, long lasting hyperthermia. This indicates that in young chicks the blood brain barrier is probably permeable to endotoxins.
摘要
- 研究了静脉注射前列腺素E1和内毒素对幼鸡（11 - 17日龄）的影响。2. 在热中性环境温度（31摄氏度）下，静脉注射前列腺素E1会产生行为性和皮层脑电图睡眠，增加耗氧量，并在最初下降后使体温升高。在低于热中性温度（16摄氏度）时，最初的低温效应更明显，耗氧量降低。3. 前列腺素E1的催眠作用足以抵消右旋苯丙胺引起的行为性和皮层脑电图觉醒及发声。4. 静脉注射痢疾志贺氏菌的O-菌体抗原，经过一段潜伏期后，会引起持久的体温过高。这表明在幼鸡中，血脑屏障可能对内毒素具有通透性。
相似文献
1
Some effects of intravenous prostaglandin E, and endotoxin in young chickens.静脉注射前列腺素E和内毒素对雏鸡的一些影响。
Br J Pharmacol. 1977 Sep;61(1):29-37. doi: 10.1111/j.1476-5381.1977.tb09736.x.
2
Some effects of prostaglandins E1 and E2 and of endotoxin injected into the hypothalamus of young chicks: dissociation between endotoxin fever and the effects of prostaglandins.前列腺素E1和E2以及内毒素注入幼雏下丘脑的某些作用：内毒素热与前列腺素作用之间的分离
Br J Pharmacol. 1977 Sep;61(1):39-46. doi: 10.1111/j.1476-5381.1977.tb09737.x.
3
Central effects of clonidine 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride in fowls.可乐定（2-（2,6-二氯苯基氨基）-2-咪唑啉盐酸盐）对家禽的中枢作用
Br J Pharmacol. 1975 Dec;55(4):459-73. doi: 10.1111/j.1476-5381.1975.tb07421.x.
4
Antipodal central effects of apomorphine and dopamine in chickens.阿扑吗啡和多巴胺对鸡的对映体中枢效应。
Neuropharmacology. 1982 Mar;21(3):249-60. doi: 10.1016/0028-3908(82)90195-2.
5
Prostaglandins, endotoxin and lipid A on body temperature in rats.前列腺素、内毒素和脂多糖对大鼠体温的影响
J Physiol. 1975 Aug;249(3):601-15. doi: 10.1113/jphysiol.1975.sp011033.
6
Fever produced by endotoxin injected into the hypothalamus of the monkey and its antagonism by salicylate.注入猴下丘脑的内毒素所产生的发热及其被水杨酸盐的拮抗作用。
J Physiol. 1974 Nov;243(1):167-93. doi: 10.1113/jphysiol.1974.sp010748.
7
Endotoxin and prostaglandin fever of newborn guinea pigs at different ambient temperatures.新生豚鼠在不同环境温度下的内毒素和前列腺素发热
Acta Physiol Acad Sci Hung. 1978;51(3):293-8.
8
Changes in body temperature produced by prostaglandins and pyrogens in the chicken.
Am J Physiol. 1976 May;230(5):1284-7. doi: 10.1152/ajplegacy.1976.230.5.1284.
9
Mode of action of alpha-methylnoradrenaline on temperature and oxygen consumption in young chickens.α-甲基去甲肾上腺素对雏鸡体温和耗氧量的作用方式
Br J Pharmacol. 1970 Apr;38(4):667-87. doi: 10.1111/j.1476-5381.1970.tb09876.x.
10
Central effects of prostaglandins E2, A1 and F2alpha in adult fowls.
Neuropharmacology. 1976 Dec;15(12):737-41. doi: 10.1016/0028-3908(76)90002-2.
引用本文的文献
1
Biomolecules Triggering Altered Food Intake during Pathogenic Challenge in Chicks.雏鸡在致病性攻击期间引发食物摄入量改变的生物分子。
J Poult Sci. 2023 Mar 1;60(2):2023009. doi: 10.2141/jpsa.2023009. eCollection 2023.
2
Prostaglandins and the central nervous system.前列腺素与中枢神经系统
Postgrad Med J. 1977 Nov;53(625):649-51. doi: 10.1136/pgmj.53.625.649.
本文引用的文献
1
ACTIONS OF PROSTAGLANDINS E1, E2 AND E3 ON THE CENTRAL NERVOUS SYSTEM.前列腺素E1、E2和E3对中枢神经系统的作用。
Br J Pharmacol Chemother. 1964 Feb;22(1):189-92. doi: 10.1111/j.1476-5381.1964.tb01558.x.
2
The development of the bloodbrain barrier.血脑屏障的发育。
J Neurochem. 1957;1(3):216-27. doi: 10.1111/j.1471-4159.1957.tb12075.x.
3
Methods for quantifying behaviour and cerebral electrical activity and the effect of drugs under controlled conditions.在可控条件下量化行为、脑电活动及药物作用的方法。
Br J Pharmacol Chemother. 1965 Dec;25(3):671-81. doi: 10.1111/j.1476-5381.1965.tb01792.x.
4
The effects of cold and prostaglandin E1 on lipid mobilization in the chicken.
Can J Physiol Pharmacol. 1971 May;49(5):394-8. doi: 10.1139/y71-046.
5
Central effects of prostaglandin E1 in adult fowls.
Neuropharmacology. 1973 Nov;12(11):1009-16. doi: 10.1016/0028-3908(73)90045-2.
6
Proceedings: Hyper- and hypothermic effects of prostaglandin E-1 (PGE-1), and their potentiation by indomethacin, in chicks.
J Physiol. 1974 Oct;242(2):141P-142P.
7
Changes in body temperature produced by prostaglandins and pyrogens in the chicken.
Am J Physiol. 1976 May;230(5):1284-7. doi: 10.1152/ajplegacy.1976.230.5.1284.
8
Prostaglandins, endotoxin and lipid A on body temperature in rats.前列腺素、内毒素和脂多糖对大鼠体温的影响
J Physiol. 1975 Aug;249(3):601-15. doi: 10.1113/jphysiol.1975.sp011033.
9
Effects of noradrenaline infused into the chick hypothalamus on thermoregulation below thermoneutrality.将去甲肾上腺素注入雏鸡下丘脑对低于热中性温度时体温调节的影响。
J Physiol. 1975 Feb;245(2):289-303. doi: 10.1113/jphysiol.1975.sp010846.
10
Some effects of prostaglandins E1 and E2 and of endotoxin injected into the hypothalamus of young chicks: dissociation between endotoxin fever and the effects of prostaglandins.前列腺素E1和E2以及内毒素注入幼雏下丘脑的某些作用：内毒素热与前列腺素作用之间的分离
Br J Pharmacol. 1977 Sep;61(1):39-46. doi: 10.1111/j.1476-5381.1977.tb09737.x.
Zotero 插件