Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, China.
Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430022, Wuhan, China.
BMC Ophthalmol. 2021 Jan 11;21(1):29. doi: 10.1186/s12886-020-01792-4.
To investigate the microbiologic spectrum of dacryocystitis in adult and pediatric groups, specifically the microbiologic differences between chronic dacryocystitis with nasolacrimal duct obstruction (NLDO) and acute dacryocystitis in pediatric group.
This retrospective study was reviewed for demographic and microbiologic profile of dacryocystitis. The culture results were reported.
Sixty-four adults and one hundred and five pediatrics with dacryocystitis were included in this study. Of all adults, only chronic dacryocystitis with NLDO was observed. Of all pediatric patients, 89 had chronic dacryocystitis with NLDO and 16 had acute dacryocystitis. Gram positive and negative isolates were numerically equal in adult group (both 36(48.65%)), while gram positive isolates were the major organism in pediatric group (71(58.68%)). Streptococcus pneumonia was the most common isolate in both adult (11(14.86%)) and pediatric (30(24.79%)) dacryocystitis. For both pediatric subgroups, gram positive isolates were the major organism (59(57.84%) for chronic dacryocystitis with NLDO and 12 (63.16%) for acute dacryocystitis). However, the leading isolates in those two subgroups were distinct, with Streptococcus pneumonia (29(28.43%)) being most common in chronic dacryocystitis with NLDO and Staphylococcus aureus (8(42.11%)) being most common in acute dacryocystitis.
In adult group, gram negative isolates were more common in dacryocystitis than before. In pediatric group, gram positive isolates were still the major infection pathogen. Moreover, the more virulent organisms were more common in acute dacryocystitis than chronic dacryocystitis with NLDO.
为了研究成人和儿童泪囊炎的微生物谱，特别是慢性泪囊炎伴鼻泪管阻塞（NLDO）和儿童急性泪囊炎之间的微生物学差异。
本回顾性研究分析了泪囊炎患者的人口统计学和微生物学特征。报告了培养结果。
本研究共纳入 64 例成人和 105 例儿科泪囊炎患者。所有成人患者均为慢性泪囊炎伴 NLDO。所有儿科患者中，89 例为慢性泪囊炎伴 NLDO，16 例为急性泪囊炎。成人组革兰阳性和革兰阴性分离株数量相等（均为 36 株（48.65%）），而革兰阳性分离株是儿科组的主要病原体（71 株（58.68%））。肺炎链球菌是成人（11 株（14.86%））和儿科（30 株（24.79%））泪囊炎中最常见的分离株。对于儿科两个亚组，革兰阳性分离株是主要病原体（慢性泪囊炎伴 NLDO 中为 59 株（57.84%），急性泪囊炎中为 12 株（63.16%））。然而，这两个亚组的主要病原体不同，肺炎链球菌（29 株（28.43%））在慢性泪囊炎伴 NLDO 中最为常见，金黄色葡萄球菌（8 株（42.11%））在急性泪囊炎中最为常见。
在成人组中，与之前相比，革兰氏阴性分离株在泪囊炎中更为常见。在儿科组中，革兰氏阳性分离株仍然是主要感染病原体。此外，急性泪囊炎比慢性泪囊炎伴 NLDO 中更为常见的是毒力更强的病原体。
