Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China; Center for Pathogen Research, West China Hospital, Sichuan University, Chengdu, China; Department of Infection Control, West China Hospital, Sichuan University, Chengdu, China; Division of Infectious Diseases, State Key Laboratory of Biotherapy, Chengdu, China.
Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China; Center for Pathogen Research, West China Hospital, Sichuan University, Chengdu, China; Division of Infectious Diseases, State Key Laboratory of Biotherapy, Chengdu, China.
Trends Microbiol. 2021 Jun;29(6):473-476. doi: 10.1016/j.tim.2020.12.009. Epub 2021 Jan 8.
Enterobacter is a globally important pathogen. Here we clarify its taxonomy and review recent developments in its resistance to carbapenem and colistin, illustrating that Enterobacter has a large arsenal of mechanisms to grow under antimicrobial pressure. Further studies are required to decipher colistin heteroresistance and understand why certain Enterobacter lineages have emerged clinically.
肠杆菌属是一种具有全球重要意义的病原体。在这里，我们阐明了其分类学，并回顾了其对碳青霉烯类和黏菌素类药物耐药性的最新进展，表明肠杆菌属拥有大量的机制来在抗菌药物压力下生长。需要进一步的研究来解析黏菌素异质性耐药性，并了解为什么某些肠杆菌属谱系在临床上出现。
