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通用 COVID-19 筛查方案对无症状肿瘤患者的结果和影响。

Outcomes and Impact of a Universal COVID-19 Screening Protocol for Asymptomatic Oncology Patients.

机构信息

Oncology Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.

Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.

出版信息

Gulf J Oncolog. 2020 Sep;1(34):7-12.

Abstract

INTRODUCTION

COVID-19 has become a serious hazard worldwide in a relatively short time. Scientific evidence supports that cancer patients infected with COVID-19 had a higher risk of developing severe complications. COVID-19 patients can be asymptomatic during part or all of their disease course, therefore it is a compelling need to develop universal pre-interventional COVID-19 screening guidelines. The aim of this study is to is review COVID-19 positive rate among asymptomatic cancer patients since the implementation of universal policy at our institution, and assess the impact of diagnosing COVID-19 on delay of oncologic interventions.

MATERIALS AND METHODS

The study population comprised of all cancer patients planned for high risk interventions between April 1, 2020 - May 14, 2020 at Cleveland Clinic Abu Dhabi [CCAD] after implementing universal COVID-19 screening policy.

DISCUSSION

Nosocomial transmission of COVID-19 among cancer patients could result in poor outcomes. Universal screening for high-risk populations may facilitate earlier diagnosis of COVID-19 and implementation of control strategies. Our review demonstrated that [7.5%] of asymptomatic cancer patients tested positive for COVID-19 after implementation of universal prospective screening policy. The overall evidence supporting universal COVID-19 screening of cancer patients is limited, yet as tests become more widely available, it may be reasonable to screen all cancer patients for COVID-19 before anticancer therapies. While such policy may delay and affect the timing of anticancer therapy as shown in this report, it should improve the safety of care for oncology patients and help protect healthcare workers.

CONCLUSION

COVID-19 infection rate is higher in cancer patients than general population and can present without symptoms. Universal COVID-19 screening of cancer patients before high risk interventions is supported by the present findings.

摘要

简介

COVID-19 在相对较短的时间内已成为全球范围内的严重危害。科学证据表明,感染 COVID-19 的癌症患者发生严重并发症的风险更高。COVID-19 患者在其疾病过程的部分或全部时间可能无症状,因此制定普遍的预干预 COVID-19 筛查指南是当务之急。本研究旨在回顾我院实施普遍政策以来无症状癌症患者 COVID-19 阳性率,并评估诊断 COVID-19 对肿瘤干预延迟的影响。

材料和方法

研究人群包括 2020 年 4 月 1 日至 5 月 14 日在阿布扎比克利夫兰诊所(CCAD)实施普遍 COVID-19 筛查政策后计划进行高危干预的所有癌症患者。

讨论

COVID-19 在癌症患者中的医院内传播可能导致不良后果。对高危人群进行普遍筛查可能有助于及早诊断 COVID-19 并实施控制策略。我们的回顾表明,在实施普遍前瞻性筛查政策后,[7.5%]的无症状癌症患者 COVID-19 检测呈阳性。普遍筛查癌症患者 COVID-19 的总体证据有限,但随着检测的广泛应用,在接受抗癌治疗之前对所有癌症患者进行 COVID-19 筛查可能是合理的。虽然这种政策可能会像本报告所示那样延迟和影响抗癌治疗的时机,但它应该会提高肿瘤患者护理的安全性,并有助于保护医护人员。

结论

癌症患者 COVID-19 感染率高于一般人群,且可能无症状。本研究结果支持对癌症患者进行高危干预前进行普遍 COVID-19 筛查。

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