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蛋白丢失性肠病作为炎症性肠病的前驱:文献复习。

Protein-losing enteropathy as precursor of inflammatory bowel disease: a review of the literature.

机构信息

Department for Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland

Department for Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland.

出版信息

BMJ Case Rep. 2021 Jan 11;14(1):e238802. doi: 10.1136/bcr-2020-238802.

Abstract

We report the case of a 63-year-old female patient with liver cirrhosis who presented with symptoms of severe hypoalbuminaemia and diarrhoea. After ruling out other causes of hypoalbuminaemia and confirmation of an elevated faecal α-1 antitrypsin clearance, the diagnosis of protein-losing enteropathy (PLE) could be established. Since PLE is a syndrome caused by various diseases, classified into erosive and non-erosive gastrointestinal diseases or lymphatic obstruction, an extensive work-up was necessary, establishing the final diagnosis of Crohn's disease.

摘要

我们报告了一例 63 岁女性肝硬化患者,其表现为严重低白蛋白血症和腹泻。在排除其他低白蛋白血症的原因并确认粪便 α-1 抗胰蛋白酶清除率升高后,可以确诊为蛋白丢失性肠病(PLE)。由于 PLE 是由各种疾病引起的综合征,分为侵蚀性和非侵蚀性胃肠道疾病或淋巴阻塞,因此需要进行广泛的检查,最终诊断为克罗恩病。

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