Department for Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland
Department for Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland.
BMJ Case Rep. 2021 Jan 11;14(1):e238802. doi: 10.1136/bcr-2020-238802.
We report the case of a 63-year-old female patient with liver cirrhosis who presented with symptoms of severe hypoalbuminaemia and diarrhoea. After ruling out other causes of hypoalbuminaemia and confirmation of an elevated faecal α-1 antitrypsin clearance, the diagnosis of protein-losing enteropathy (PLE) could be established. Since PLE is a syndrome caused by various diseases, classified into erosive and non-erosive gastrointestinal diseases or lymphatic obstruction, an extensive work-up was necessary, establishing the final diagnosis of Crohn's disease.
我们报告了一例 63 岁女性肝硬化患者,其表现为严重低白蛋白血症和腹泻。在排除其他低白蛋白血症的原因并确认粪便 α-1 抗胰蛋白酶清除率升高后,可以确诊为蛋白丢失性肠病(PLE)。由于 PLE 是由各种疾病引起的综合征,分为侵蚀性和非侵蚀性胃肠道疾病或淋巴阻塞,因此需要进行广泛的检查,最终诊断为克罗恩病。