Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, University of Health Sciences, İstasyon Mah, Turgut Özal Bulvari No:11, 34303, Küçükçekmece/Istanbul, Turkey.
Department of Nephrology, Dr Lutfi Kirdar Kartal Educational and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Herz. 2021 Feb;46(1):56-62. doi: 10.1007/s00059-020-05014-x. Epub 2021 Jan 12.
The goal of the present work was to examine associations between COVID-19 pneumonia severity and pulmonary artery diameter. A total of 101 patients with COVID-19 were included in this retrospective observational study. The patients were divided into three groups based on the CT images: 41 patients with mild pneumonia, group 2 had 39 patients with moderate pneumonia, and group 3 had 21 patients with severe pneumonia. Furthermore, the diameter of the main pulmonary artery was calculated as well as ascending aorta, right and left pulmonary artery diameters. Laboratory analysis results were also compared. Analyses show an increased main pulmonary artery diameter is associated with poorer prognosis for patients with COVID-19 pneumonia. Further studies are needed into the mechanisms between severe hypoxemia, increased inflammation, and vascular resistance and higher numbers of thromboembolic events.
本研究旨在探讨 COVID-19 肺炎严重程度与肺动脉直径之间的相关性。这项回顾性观察研究共纳入 101 例 COVID-19 患者。根据 CT 图像，患者被分为三组：41 例轻度肺炎患者为组 1，39 例中度肺炎患者为组 2，21 例重度肺炎患者为组 3。此外，还计算了主肺动脉直径以及升主动脉、右肺动脉和左肺动脉直径。比较了实验室分析结果。分析表明，主肺动脉直径增大与 COVID-19 肺炎患者预后不良相关。需要进一步研究严重低氧血症、炎症增加和血管阻力与更高数量的血栓栓塞事件之间的机制。
