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Immune Biology of Acute Myeloid Leukemia: Implications for Immunotherapy.

作者信息

Khaldoyanidi Sophia, Nagorsen Dirk, Stein Anthony, Ossenkoppele Gerrit, Subklewe Marion

机构信息

Amgen, Thousand Oaks, CA.

City of Hope Comprehensive Cancer Center, Duarte, CA.

出版信息

J Clin Oncol. 2021 Feb 10;39(5):419-432. doi: 10.1200/JCO.20.00475. Epub 2021 Jan 12.

DOI:10.1200/JCO.20.00475
PMID:33434043
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8078464/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ec/8078464/8fb71f7f5644/jco-39-419-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ec/8078464/8fb71f7f5644/jco-39-419-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ec/8078464/8fb71f7f5644/jco-39-419-g001.jpg

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Preclinical Evaluation of B7-H3-specific Chimeric Antigen Receptor T Cells for the Treatment of Acute Myeloid Leukemia.B7-H3 特异性嵌合抗原受体 T 细胞治疗急性髓系白血病的临床前评估。
Clin Cancer Res. 2021 Jun 1;27(11):3141-3153. doi: 10.1158/1078-0432.CCR-20-2540. Epub 2021 Feb 2.
2
Bispecific and split CAR T cells targeting CD13 and TIM3 eradicate acute myeloid leukemia.双特异性和分裂嵌合抗原受体 T 细胞靶向 CD13 和 TIM3 根除急性髓系白血病。
Blood. 2020 Mar 5;135(10):713-723. doi: 10.1182/blood.2019002779.
3
The role of allogeneic stem cell transplantation in the management of acute myeloid leukaemia: a triumph of hope and experience.
白血病的miRNA全景——通过分子机制实现细胞作用以进行治疗
Cell Biochem Biophys. 2025 Jul 18. doi: 10.1007/s12013-025-01820-4.
4
Abnormal metabolic activation of CD8 T cells correlates with poor prognosis in acute myeloid leukemia.CD8 T细胞的异常代谢激活与急性髓系白血病的不良预后相关。
J Transl Med. 2025 Jul 14;23(1):791. doi: 10.1186/s12967-025-06833-4.
5
Mesenchymal stem cells in the bone marrow microenvironment: a double-edged sword for AML.骨髓微环境中的间充质干细胞:急性髓系白血病的双刃剑
J Cancer Res Clin Oncol. 2025 Jun 21;151(6):193. doi: 10.1007/s00432-025-06244-4.
6
Blastemia portrays a poor prognosis in acute leukemia patients with invasive pulmonary aspergillosis.在患有侵袭性肺曲霉病的急性白血病患者中,母细胞血症预示着预后不良。
J Infect. 2025 Aug;91(2):106535. doi: 10.1016/j.jinf.2025.106535. Epub 2025 Jun 16.
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Front Pediatr. 2025 May 9;13:1589770. doi: 10.3389/fped.2025.1589770. eCollection 2025.
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Curr Opin Pharmacol. 2025 Jun;82:102526. doi: 10.1016/j.coph.2025.102526. Epub 2025 Apr 8.
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