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各种白细胞介素在急性髓系白血病中的作用。

The role of various interleukins in acute myeloid leukemia.

机构信息

Department of Microbiology, Immunology and Pathology, Des Moines University College of Osteopathic Medicine, Des Moines, IA, 50312, USA.

The Department of Respiratory Medicine, The 2nd People's Hospital of Hefei and Hefei Hospital Affiliated to Anhui Medical University, Hefei, China.

出版信息

Med Oncol. 2021 Apr 9;38(5):55. doi: 10.1007/s12032-021-01498-7.

Abstract

Interleukins are signaling molecules involved in the immune system, and they play a variety of roles in different diseases and cancers. Acute myeloid leukemia (AML) is the most common type of leukemia in adults, and survival rate after diagnosis is very low. Investigating the role interleukins play in AML can help understand the progression of the disease. There exists a need for more effective treatment of AML. Interleukins can be used to guide immunotherapy for AML. This review article will examine how specific interleukins play a role in AML disease progression and how they can be utilized as a future treatment option.

摘要

白细胞介素是参与免疫系统的信号分子,它们在不同的疾病和癌症中发挥着多种作用。急性髓细胞白血病(AML)是成人中最常见的白血病类型,诊断后的生存率非常低。研究白细胞介素在 AML 中的作用有助于了解疾病的进展。目前需要更有效的 AML 治疗方法。白细胞介素可用于指导 AML 的免疫治疗。本文综述将探讨特定白细胞介素在 AML 疾病进展中的作用以及如何将其作为未来的治疗选择。

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