IEEE J Biomed Health Inform. 2021 Aug;25(8):2848-2856. doi: 10.1109/JBHI.2021.3050113. Epub 2021 Aug 5.
Obstructive Sleep Apnea (OSA) is a highly prevalent but inconspicuous disease that seriously jeopardizes the health of human beings. Polysomnography (PSG), the gold standard of detecting OSA, requires multiple specialized sensors for signal collection, hence patients have to physically visit hospitals and bear the costly treatment for a single detection. Recently, many single-sensor alternatives have been proposed to improve the cost efficiency and convenience. Among these methods, solutions based on RR-interval (i.e., the interval between two consecutive pulses) signals reach a satisfactory balance among comfort, portability and detection accuracy. In this paper, we advance RR-interval based OSA detection by considering its real-world practicality from energy perspectives. As photoplethysmogram (PPG) pulse sensors are commonly equipped on smart wrist-worn wearable devices (e.g., smart watches and wristbands), the energy efficiency of the detection model is crucial to fully support an overnight observation on patients. This creates challenges as the PPG sensors are unable to keep collecting continuous signals due to the limited battery capacity on smart wrist-worn devices. Therefore, we propose a novel Frequency Extraction Network (FENet), which can extract features from different frequency bands of the input RR-interval signals and generate continuous detection results with downsampled, discontinuous RR-interval signals. With the help of the one-to-multiple structure, FENet requires only one-third of the operation time of the PPG sensor, thus sharply cutting down the energy consumption and enabling overnight diagnosis. Experimental results on real OSA datasets reveal the state-of-the-art performance of FENet.
阻塞性睡眠呼吸暂停(OSA)是一种高发但隐匿的疾病,严重危害人类健康。多导睡眠图(PSG)是检测 OSA 的金标准,需要多个专用传感器进行信号采集,因此患者必须亲自到医院就诊,并为单次检测支付昂贵的费用。最近,许多单传感器替代方案被提出,以提高成本效益和便利性。在这些方法中,基于 RR 间隔(即两个连续脉冲之间的间隔)信号的解决方案在舒适性、便携性和检测准确性之间达到了令人满意的平衡。在本文中,我们从能量角度考虑 RR 间隔信号的实际应用,来推进基于 RR 间隔的 OSA 检测。由于光体积描记图(PPG)脉搏传感器通常配备在智能腕戴式可穿戴设备(如智能手表和腕带)上,检测模型的能量效率对于完全支持对患者进行整夜观察至关重要。由于智能腕戴式设备的电池容量有限,PPG 传感器无法连续采集信号,这就带来了挑战。因此,我们提出了一种新的频率提取网络(FENet),它可以从输入 RR 间隔信号的不同频带中提取特征,并使用下采样、不连续的 RR 间隔信号生成连续的检测结果。借助一对一多结构,FENet 仅需要 PPG 传感器三分之一的操作时间,从而大幅降低能耗,实现整夜诊断。在真实 OSA 数据集上的实验结果表明了 FENet 的卓越性能。