缺血性脊髓损伤——实验证据与保护措施的进展
Ischemic Spinal Cord Injury-Experimental Evidence and Evolution of Protective Measures.
作者信息
Khachatryan Zara, Haunschild Josephina, von Aspern Konstantin, Borger Michael A, Etz Christian D
机构信息
University Department for Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
University Department for Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
出版信息
Ann Thorac Surg. 2022 May;113(5):1692-1702. doi: 10.1016/j.athoracsur.2020.12.028. Epub 2021 Jan 9.
BACKGROUND
Paraplegia remains one of the most devastating complications of descending and thoracoabdominal aortic repair. The aim of this review is to outline the current state of art in the rapidly developing field of spinal cord injury research.
METHODS
A review of PubMed and Web of Science databases was performed using the following terms and their combinations: spinal cord, injury, ischemia, ischemia-reperfusion, ischemic spinal cord injury, paraplegia, paraparesis. Articles published before July 2019 were screened and included if considered relevant.
RESULTS
The review focuses on the topic of spinal cord injury and the developments concerning methods of monitoring, diagnosing, and preventing spinal cord injury.
CONCLUSIONS
Translation of novel technologies from bench to bedside and into everyday clinical practice is challenging; however, each of the developing areas holds great promise in spinal cord injury prevention.
背景
截瘫仍然是降主动脉和胸腹主动脉修复最具毁灭性的并发症之一。本综述的目的是概述脊髓损伤研究快速发展领域的当前技术水平。
方法
使用以下术语及其组合对PubMed和Web of Science数据库进行检索：脊髓、损伤、缺血、缺血再灌注、缺血性脊髓损伤、截瘫、轻截瘫。筛选2019年7月之前发表的文章，若认为相关则纳入。
结果
本综述聚焦于脊髓损伤主题以及脊髓损伤监测、诊断和预防方法的进展。
结论
将新技术从实验室转化到临床床边并应用于日常临床实践具有挑战性；然而，每个发展领域在预防脊髓损伤方面都具有巨大潜力。
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