Woody R C, Brodie M, Hampton D K, Fiser R H
Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock.
J Child Neurol. 1988 Jan;3(1):21-4. doi: 10.1177/088307388800300103.
The ketogenic diet is a well-established, but relatively infrequently used, therapy for intractable seizures in children. Currently, the standard ketogenic diet is formulated using medium chain triglyceride (MCT) oil as its major caloric source. Cost, availability, and gastrointestinal side effects limit its use in some cases. We report the successful substitution of corn oil for MCT oil in six children treated with the ketogenic diet for intractable seizures. In each case, the corn oil ketogenic diet was effective, well-tolerated by the patient and parents, and free of clinical toxicity. Corn oil also has the major advantages of being much less expensive and more available that MCT oil. Its use in the ketogenic diet appears to be effective, safe, and practical.
生酮饮食是一种已被广泛认可但相对较少使用的治疗儿童难治性癫痫的方法。目前，标准生酮饮食以中链甘油三酯（MCT）油作为主要热量来源。成本、可得性和胃肠道副作用在某些情况下限制了其应用。我们报告了6例接受生酮饮食治疗难治性癫痫的儿童成功用玉米油替代MCT油的情况。在每例病例中，玉米油生酮饮食均有效，患者和家长耐受性良好，且无临床毒性。玉米油还具有比MCT油便宜得多且更容易获得的主要优势。其在生酮饮食中的应用似乎有效、安全且实用。
