促黄体生成素腺瘤导致不孕妇女手术后成功妊娠：病例报告及文献复习。
Successful pregnancy after operation in an infertile woman caused by luteinizing hormone-secreting pituitary adenoma: case report and literature review.
机构信息
Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, 100730, China.
Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
出版信息
BMC Endocr Disord. 2021 Jan 12;21(1):15. doi: 10.1186/s12902-020-00677-3.
BACKGROUND
Functional gonadotroph adenomas (FGAs) are rare adenomas that most commonly secrete FSH. However, solitary LH-secreting pituitary adenomas are unusual.
CASE PRESENTATION
A 30-year-old woman with elevated LH and normal FSH presented with inability to conceive. An MRI revealed an enlarged sella turcica and an intrasellar mass. Treatment with transsphenoidal resection led to normalization of LH and estradiol, as well as successful pregnancy. And we reviewed 6 cases of LH-secreting pituitary adenomas from 1981 to 2020.
CONCLUSIONS
Our case is unique because of the LH-secreting pituitary adenoma without FSH hypersecretion. This case indicates that pituitary adenoma should be considered when other diseases causing infertility have been excluded.
背景
功能性促性腺激素腺瘤（FGAs）是一种罕见的腺瘤，最常分泌 FSH。然而，单纯分泌 LH 的垂体腺瘤并不常见。
病例介绍
一位 30 岁的女性，LH 升高而 FSH 正常，表现为不孕。MRI 显示蝶鞍扩大和鞍内肿块。经蝶窦切除术治疗导致 LH 和雌二醇恢复正常，并成功妊娠。我们回顾了 1981 年至 2020 年的 6 例 LH 分泌性垂体腺瘤病例。
结论
我们的病例很独特，因为 LH 分泌性垂体腺瘤没有 FSH 过度分泌。该病例表明，在排除其他导致不孕的疾病后，应考虑垂体腺瘤。
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