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一例进行性外层视网膜坏死并发症的外科治疗

Surgical management of complications in a case of progressive outer retinal necrosis.

作者信息

Mehrotra Navneet, Khandelwal Jayesh, Nagpal Manish

机构信息

Department of Vitreo-Retina, Retina Foundation, Shahibaug, Ahmedabad, Gujarat, India.

出版信息

Taiwan J Ophthalmol. 2020 Mar 31;10(4):312-314. doi: 10.4103/tjo.tjo_27_19. eCollection 2020 Oct-Dec.

DOI:10.4103/tjo.tjo_27_19
PMID:33437609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7787098/
Abstract

We report a case of bilateral progressive outer retinal necrosis (PORN) in a patient with acquired immune deficiency syndrome with CD4 count 50 cells/μL. He was treated with standard intravenous and intravitreal antivirals but ultimately developed complications such as retinal detachment and epiretinal membrane. His vision was preserved with early pars plana vitrectomy. This case demonstrates that prompt clinical diagnosis of PORN with its successful medical and surgical management can help prevent progression of this frightening disease.

摘要

我们报告了一例获得性免疫缺陷综合征患者双侧进行性外层视网膜坏死（PORN）的病例，其CD4细胞计数为50个/μL。他接受了标准的静脉内和玻璃体内抗病毒治疗，但最终出现了视网膜脱离和视网膜前膜等并发症。早期玻璃体切割术使他的视力得以保留。该病例表明，对PORN进行及时的临床诊断并成功进行药物和手术治疗有助于预防这种可怕疾病的进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b91/7787098/471ee70c2db1/TJO-10-312-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b91/7787098/cb060c51eecb/TJO-10-312-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b91/7787098/aabcd783109f/TJO-10-312-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b91/7787098/471ee70c2db1/TJO-10-312-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b91/7787098/cb060c51eecb/TJO-10-312-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b91/7787098/aabcd783109f/TJO-10-312-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b91/7787098/471ee70c2db1/TJO-10-312-g003.jpg

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引用本文的文献

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The Role of Early Vitrectomy in the Healing of Retinal Lesions in Progressive Outer Retinal Necrosis.早期玻璃体切除术在进展性外层视网膜坏死中视网膜病变愈合中的作用。
Case Rep Ophthalmol Med. 2022 Feb 27;2022:7636052. doi: 10.1155/2022/7636052. eCollection 2022.

本文引用的文献

1
Progressive outer retinal necrosis: outcomes in the intravitreal era.进行性外层视网膜坏死：玻璃体腔内注射时代的治疗结果
Arch Ophthalmol. 2012 Jun;130(6):700-6. doi: 10.1001/archophthalmol.2011.2622.
2
A case of atypical progressive outer retinal necrosis after highly active antiretroviral therapy.1例高效抗逆转录病毒治疗后发生的非典型进行性外层视网膜坏死病例。
Korean J Ophthalmol. 2004 Jun;18(1):65-9. doi: 10.3341/kjo.2004.18.1.65.
3
Intravitreal antivirals in the management of patients with acquired immunodeficiency syndrome with progressive outer retinal necrosis.
玻璃体内抗病毒药物在获得性免疫缺陷综合征合并进行性外层视网膜坏死患者治疗中的应用
Arch Ophthalmol. 2002 Sep;120(9):1219-22.
4
Management of varicella zoster virus retinitis in AIDS.艾滋病患者水痘带状疱疹病毒视网膜炎的管理
Br J Ophthalmol. 1997 Mar;81(3):189-94. doi: 10.1136/bjo.81.3.189.
5
Rapidly progressive outer retinal necrosis caused by varicella zoster virus in a patient infected with human immunodeficiency virus.一名感染人类免疫缺陷病毒的患者中由水痘带状疱疹病毒引起的快速进展性外层视网膜坏死。
Clin Infect Dis. 1996 Jan;22(1):149-51. doi: 10.1093/clinids/22.1.149.
6
The progressive outer retinal necrosis syndrome. A variant of necrotizing herpetic retinopathy in patients with AIDS.进行性外层视网膜坏死综合征。艾滋病患者坏死性疱疹性视网膜病变的一种变体。
Ophthalmology. 1994 Sep;101(9):1488-502. doi: 10.1016/s0161-6420(94)31142-0.
7
Rapidly progressive outer retinal necrosis in the acquired immunodeficiency syndrome.获得性免疫缺陷综合征中的快速进展性外层视网膜坏死
Am J Ophthalmol. 1990 Oct 15;110(4):341-8. doi: 10.1016/s0002-9394(14)77012-6.