Department of Clinical Biochemistry, Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Department of Clinical Biochemistry, Lorestan University of Medical Sciences, Khorramabad, Iran.
Cardiovasc Hematol Agents Med Chem. 2022;20(3):237-250. doi: 10.2174/1871525719666210112155652.
Many pharmaceutical plants belonging to this region are used as the traditional drug by traditional physicians of the Urmia city in order to treat signs of disorders and cardiovascular system diseases.
The Ghasemloo valley located in Urmia city is one of the typical areas in northwestern Iran and includes many pharmaceutical and plant species.
Many pharmaceutical plants belonging to this region are used as the traditional drug by traditional physicians of the Urmia city in order to treat several symptoms of disorders and cardiovascular system diseases.
A study was performed among 35 grocers in Urmia city to identify effective and famous pharmaceutical plants in the treatment of cardiovascular and related diseases. Firstly, a complete list of Urmia grocers was prepared by the Food and Drug Administrator of the Urmia University of Medical Sciences. The direct observation and interview, alongside collecting herbarium samples of usual and effective indigenous medicinal plants, were used to identify disorders and different signs of cardiovascular diseases. Questionnaires included personal information of grocers, and completed indigenous plants list containing information, including the plant's local name, the used organ, method of use, and the traditional therapeutic effect. Herbarium samples mentioned in the questionnaire were collected from the region and sent to the Jahad-e-Keshavarzi Research Centers and the Agriculture Faculty of Urmia university to determine the genus and species. After identifying and confirming the plant species, data related to the plant and results of cardiovascular research conducted on them were collected and recorded with reference to valid scientific sites. Data were entered into the Excel 2010 program and then analyzed.
60 medicinal plants of 26 families in Urmia were identified as effective in the treatment of cardiovascular diseases from interviews and questionnaires; some plants mentioned in this study had known traditional therapeutic effects on cardiovascular disorders in the literature and some were identified with new effects. Results showed that the most therapeutic effects in cardiovascular diseases belonged to families Rosaceae (15%), Fabaceae (13%), Asteraceae (13%), and Apiaceae (10%). The most used organs of plants were the leave (23%) and fruit (19%). Plants were used mainly as an infusion (68%) in the traditional method. Most plants of this study were used to treat the blood cholesterol (29%), hypertension (9%), blood coagulation, prevention of bleeding (9%), and decrease in abdominal fat (9%).
Some herbs introduced in this study have new therapeutic effects introduced for the first time. It is necessary to study the therapeutic effects of indigenous plants presented in this research in order to prove studied and mentioned therapeutic effects and provide a study field for researchers in relation to identifying effective substances and studying claimed clinical effects of these plants on different cardiovascular diseases.
乌尔米亚市的传统医生常使用该地区的许多药用植物来治疗疾病症状和心血管系统疾病。
位于乌尔米亚市的加塞姆卢山谷是伊朗西北部的一个典型地区，拥有许多药用植物和植物物种。
乌尔米亚市的传统医生常使用该地区的许多药用植物来治疗疾病症状和心血管系统疾病。
对乌尔米亚市的 35 家杂货店进行了一项研究，以确定治疗心血管系统疾病和相关疾病的有效和著名的药用植物。首先，乌尔米亚大学医药品监督管理局编制了一份完整的乌尔米亚杂货店清单。采用直接观察和访谈，以及收集常用和有效的本土药用植物的标本，来确定疾病和不同心血管疾病的症状。问卷包括店主的个人信息，以及包含植物当地名称、使用器官、使用方法和传统治疗效果等信息的完整本土植物清单。问卷中提到的植物标本均从该地区采集，并送往贾哈德-克沙瓦里研究中心和乌尔米亚大学农业系，以确定属和种。在确定和确认植物物种后，收集并记录与植物相关的数据以及对其进行的心血管研究结果，参考有效科学网站。将数据输入 Excel 2010 程序，然后进行分析。
通过访谈和问卷调查，从 26 个科的 60 种药用植物中鉴定出对心血管疾病有治疗作用的植物；本研究中提到的一些植物在文献中对心血管疾病有已知的传统治疗作用，而另一些则被鉴定出具有新的作用。结果表明，在心血管疾病中最具治疗作用的是蔷薇科（15%）、豆科（13%）、菊科（13%）和伞形科（10%）。植物最常用的器官是叶（23%）和果实（19%）。植物主要以煎剂（68%）的传统方法使用。本研究中的大多数植物用于治疗胆固醇血症（29%）、高血压（9%）、血液凝固、防止出血（9%）和减少腹部脂肪（9%）。
本研究介绍的一些草药具有首次报道的新的治疗作用。有必要研究本研究中提出的本土植物的治疗作用，以验证研究和提到的治疗作用，并为研究人员提供一个研究领域，以确定这些植物对不同心血管疾病的有效物质和研究声称的临床作用。
