Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes.
作者信息
Nebbioso Angela, Manzo Fabio, Miceli Marco, Conte Mariarosaria, Manente Lucrezia, Baldi Alfonso, De Luca Antonio, Rotili Dante, Valente Sergio, Mai Antonello, Usiello Alessandro, Gronemeyer Hinrich, Altucci Lucia
出版信息
EMBO Rep. 2020 Dec 3;21(12):e51028. doi: 10.15252/embr.202051028. Epub 2020 Nov 26.
Abstract
摘要
相似文献
1
Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes.选择性II类组蛋白去乙酰化酶抑制剂通过调节组蛋白去乙酰化酶-MEF2复合物的稳定性和活性来损害肌生成。
EMBO Rep. 2020 Dec 3;21(12):e51028. doi: 10.15252/embr.202051028. Epub 2020 Nov 26.
2
Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes.选择性II类组蛋白去乙酰化酶抑制剂通过调节组蛋白去乙酰化酶-MEF2复合物的稳定性和活性来损害肌生成。
EMBO Rep. 2009 Jul;10(7):776-82. doi: 10.1038/embor.2009.88. Epub 2009 Jun 5.
3
Differential regulation of Bdnf expression in cortical neurons by class-selective histone deacetylase inhibitors.类别选择性组蛋白去乙酰化酶抑制剂对皮质神经元中脑源性神经营养因子（Bdnf）表达的差异性调控
Neuropharmacology. 2013 Dec;75:106-15. doi: 10.1016/j.neuropharm.2013.07.015. Epub 2013 Aug 2.
4
Folding of Class IIa HDAC Derived Peptides into α-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.当 IIa 类组蛋白去乙酰化酶衍生肽与与 DNA 结合的肌细胞增强因子 2 结合时，这些肽折叠成 α-螺旋。
J Mol Biol. 2024 May 1;436(9):168541. doi: 10.1016/j.jmb.2024.168541. Epub 2024 Mar 16.
5
CaM kinase IIdeltaC phosphorylation of 14-3-3beta in vascular smooth muscle cells: activation of class II HDAC repression.血管平滑肌细胞中钙调蛋白激酶IIdeltaC对14-3-3β的磷酸化作用：II类组蛋白去乙酰化酶抑制的激活
Mol Cell Biochem. 2003 Jan;242(1-2):153-61.
6
A dynamic role for HDAC7 in MEF2-mediated muscle differentiation.组蛋白去乙酰化酶7在MEF2介导的肌肉分化中的动态作用。
J Biol Chem. 2001 May 18;276(20):17007-13. doi: 10.1074/jbc.M101508200. Epub 2001 Mar 8.
7
The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis.转录共抑制因子MITR是一种对信号有反应的成肌抑制因子。
Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7354-9. doi: 10.1073/pnas.131198498. Epub 2001 Jun 5.
8
Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases.通过MEF2转录因子与II类组蛋白去乙酰化酶的结合来调节骨骼肌生成。
Mol Cell. 2000 Aug;6(2):233-44. doi: 10.1016/s1097-2765(00)00025-3.
9
HDAC-class II specific inhibition involves HDAC proteasome-dependent degradation mediated by RANBP2.II类组蛋白去乙酰化酶特异性抑制涉及由RANBP2介导的蛋白酶体依赖性组蛋白去乙酰化酶降解。
Biochim Biophys Acta. 2008 Oct;1783(10):2030-8. doi: 10.1016/j.bbamcr.2008.07.007. Epub 2008 Jul 22.
10
SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes.SIK1是一种促进骨骼肌细胞存活的II类组蛋白去乙酰化酶激酶。
Nat Med. 2007 May;13(5):597-603. doi: 10.1038/nm1573. Epub 2007 Apr 29.
引用本文的文献
1
A Comprehensive Bioinformatic Analysis Based on Functional Studies of MEF-2 Family in NSCLC.基于非小细胞肺癌中MEF-2家族功能研究的综合生物信息学分析
Yale J Biol Med. 2025 Jun 30;98(2):117-134. doi: 10.59249/PMMF2985. eCollection 2025 Jun.
2
Selective inhibition of HDAC class IIA as therapeutic intervention for KMT2A-rearranged acute lymphoblastic leukemia.选择性抑制 HDAC ⅡA 类作为治疗 KMT2A 重排急性淋巴细胞白血病的方法。
Commun Biol. 2024 Oct 4;7(1):1257. doi: 10.1038/s42003-024-06916-w.
3
Epigenetic regulation in cardiovascular disease: mechanisms and advances in clinical trials.心血管疾病中的表观遗传调控：机制与临床试验进展。
Signal Transduct Target Ther. 2022 Jun 25;7(1):200. doi: 10.1038/s41392-022-01055-2.
Zotero 插件