Department of Urology, University of California, Irvine, Orange, California, USA.
J Endourol. 2021 Jun;35(6):840-846. doi: 10.1089/end.2020.0675. Epub 2021 Jan 15.
The advent of single-use disposable flexible ureteroscopes allows for rapid prototyping of novel endoscopes. In this regard, we sought to develop a female-specific ureteroscope, with a shorter working length, to account for the female anatomy. We hypothesized that the shorter, female-specific single-use flexible ureteroscope would engender higher irrigation flow at a given pressure than that of the standard-length ureteroscope. An analysis of a standard 65 cm Dornier Axis™ ureteroscope and a shorter, 45 cm female-specific Dornier Axis ureteroscope was performed. All other aspects of the endoscopes were identical. Each ureteroscope was oriented vertically and connected to a Thermedx irrigation system to provide uniform pressurized flow. The average flow rate was computed over five, 2-minute periods at pressure settings of 50, 100, 150, and 200 mm Hg. Data were collected with the working channel unoccupied, after placement of a 200 μm (0.6F) holmium laser fiber and after passage of a 1.7F stone basket. The procedure was then repeated with the endoscopes at maximum deflection. The female gender ureteroscope had significantly higher irrigation flow rates than the standard-length ureteroscope under all conditions by an average of 11% ( < 0.02). The highest average percent increase, 17% ( < 0.001), was seen with the 1.7F NGage basket in the working channel with the endoscope straight. The maximum angle of deflection was not significantly different between the female gender and standard ureteroscopes with an open working channel (314° 315°, = 0.86), with the 1.7F NGage basket in place (314° 315°, = 0.15), and with the 200 μm holmium laser in place (316° 309°, = 0.09). A 45 cm female gender ureteroscope allows for a higher irrigation flow rate than the standard-length ureteroscope under all test conditions. There is no added benefit with regard to deflection capabilities.
一次性使用柔性输尿管镜的出现允许快速原型设计新型内窥镜。在这方面,我们试图开发一种更短的工作长度的女性专用输尿管镜,以适应女性解剖结构。我们假设,更短的、女性专用的一次性使用柔性输尿管镜在给定压力下会产生比标准长度输尿管镜更高的冲洗流量。
对标准的 65cm Dornier Axis™输尿管镜和更短的 45cm 女性专用 Dornier Axis 输尿管镜进行了分析。内窥镜的所有其他方面都是相同的。每个输尿管镜都垂直放置,并连接到 Thermedx 冲洗系统,以提供均匀的加压流量。在 50、100、150 和 200mm Hg 的压力设置下,计算了五个 2 分钟时间段的平均流量。在工作通道未占用、放置 200μm(0.6F)钬激光光纤后和通过 1.7F 结石篮后收集数据。然后在最大偏转角下重复该过程。
在所有条件下,女性专用输尿管镜的冲洗流量均明显高于标准长度输尿管镜,平均高出 11%(<0.02)。在工作通道中放置 1.7F NGage 篮且输尿管镜笔直的情况下,平均增幅最高,为 17%(<0.001)。在开放工作通道时,女性专用输尿管镜和标准输尿管镜的最大偏转角没有显著差异(314° 315°, = 0.86),放置 1.7F NGage 篮时(314° 315°, = 0.15),放置 200μm 钬激光时(316° 309°, = 0.09)。
45cm 女性专用输尿管镜在所有测试条件下的冲洗流量均高于标准长度输尿管镜。在偏转角能力方面没有额外的好处。