Heravi Farzin, Bagheri Hossein, Rangrazi Abdolrasoul, Zebarjad Seyed Mojtaba
Dental Research Center, Department of Orthodontics, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
Dental Materials Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
ACS Biomater Sci Eng. 2016 Nov 14;2(11):1867-1871. doi: 10.1021/acsbiomaterials.6b00204. Epub 2016 Sep 2.
The improvement of mechanical and antibacterial properties of glass ionomer cements (GICs) is an important goal in dental research. In this way, modification of GIC with caries preventive and remineralizing materials such as casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) is a new strategy to enhance its anticariogenic properties and the remineralization of teeth. However, one main concern is that adding CPP-ACP may have negative effects on the mechanical properties of GIC. This study investigated the influence of adding CPP-ACP on the wear rate (in the presence of artificial saliva) and compressive strength of luting and lining glass ionomer cement. CPP-ACP was incorporated into a luting and lining glass ionomer cement at different percentages (1, 1.56, and 2%). Wear rate and compressive strength were measured for each group using Pin-on-Disk tribometer device (in artificial saliva condition) and universal testing machine, respectively. The wear test was carried out in the presence of artificial saliva for better simulation of the oral environment. Our results demonstrated that increasing the percentage of CPP-ACP from 0 up to 1.56% (w/w), caused a decrease of 19% in the wear rate. However, at 2% (w/w) CPP-ACP, the wear rate increased. Compressive strength was improved by 31% when the CPP-ACP concentration was increased to 1.56% (w/w), but decreased when the concentration was raised to 2% (w/w). In conclusion, adding 1.56% CPP-ACP into luting and lining glass ionomer cement appears to provide an acceptable combination of two important mechanical properties, compressive strength and wear rate.
提高玻璃离子水门汀(GICs)的机械性能和抗菌性能是牙科研究的一个重要目标。通过这种方式,用诸如酪蛋白磷酸肽 - 无定形磷酸钙(CPP - ACP)等防龋和再矿化材料对GIC进行改性是增强其防龋性能和牙齿再矿化的一种新策略。然而,一个主要问题是添加CPP - ACP可能会对GIC的机械性能产生负面影响。本研究调查了添加CPP - ACP对粘结和衬层玻璃离子水门汀在人工唾液存在下的磨损率以及抗压强度的影响。将不同百分比(1%、1.56%和2%)的CPP - ACP掺入粘结和衬层玻璃离子水门汀中。分别使用销盘摩擦磨损试验机(在人工唾液条件下)和万能试验机对每组的磨损率和抗压强度进行测量。在人工唾液存在的情况下进行磨损试验,以更好地模拟口腔环境。我们的结果表明,将CPP - ACP的百分比从0增加到1.56%(w/w),磨损率降低了19%。然而,当CPP - ACP为2%(w/w)时,磨损率增加。当CPP - ACP浓度增加到1.56%(w/w)时,抗压强度提高了31%,但当浓度提高到2%(w/w)时,抗压强度降低。总之,在粘结和衬层玻璃离子水门汀中添加1.56%的CPP - ACP似乎能使抗压强度和磨损率这两个重要的机械性能达到可接受的组合。