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低危心脏手术中的大多数死亡本是可以避免的。

Most deaths in low-risk cardiac surgery could be avoidable.

机构信息

Department of Cardiovascular Surgery, Universidade de São Paulo Instituto do Coração (INCOR), São Paulo, São Paulo, Brazil.

Department of Cardiovascular Surgery, Hospital Samaritano Paulista, São Paulo, São Paulo, Brazil.

出版信息

Sci Rep. 2021 Jan 13;11(1):1045. doi: 10.1038/s41598-020-80175-7.

Abstract

It is observed that death rates in cardiac surgery has decreased, however, root causes that behave like triggers of potentially avoidable deaths (AD), especially in low-risk patients (less bias) are often unknown and underexplored, Phase of Care Mortality Analysis (POCMA) can be a valuable tool to identify seminal events (SE), providing valuable information where it is possible to make improvements in the quality and safety of future procedures. Our results show that in São Paul State, only one third of AD in low-risk cardiac surgery was related to specific surgical problems. After a revisited analysis, 75% of deaths could have been avoided, which in the pre-operative phase, the SE was related judgment, patient evaluation and preparation. In the intra-operative phase, most occurrences could have been avoided if other surgical technique had been used. Sepsis was responsible for 75% of AD in the intensive care unit. In the ward phase, the recognition/management of clinical decompensations and sepsis were the contributing factors. Logistic regression model identified age, previous coronary stent implantation, coronary artery bypass grafting + heart valve surgery, ≥ 2 combined heart valve surgery and hospital-acquired infection as independent predictors of AD.

摘要

尽管心脏外科手术的死亡率有所下降,但潜在可预防死亡(AD)的根本原因,尤其是在低风险患者(低偏差)中,往往是未知和未充分探索的。治疗阶段死亡率分析(POCMA)可以成为识别关键事件(SE)的有用工具,提供有价值的信息,以便在未来的手术中提高质量和安全性。我们的研究结果表明,在圣保罗州,低风险心脏手术中只有三分之一的 AD 与特定的手术问题有关。经过重新分析,75%的死亡是可以避免的,其中在术前阶段,SE 与判断、患者评估和准备有关。在手术过程中,如果使用其他手术技术,大多数情况是可以避免的。脓毒症是重症监护病房 AD 的主要原因。在病房阶段,临床失代偿和脓毒症的识别/管理是促成因素。逻辑回归模型确定了年龄、先前的冠状动脉支架植入、冠状动脉旁路移植术+心脏瓣膜手术、≥2 种联合心脏瓣膜手术和医院获得性感染是 AD 的独立预测因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02df/7806717/673e330d183a/41598_2020_80175_Fig1_HTML.jpg

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