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口服糖皮质激素治疗复发性肉芽肿性垂体炎的病例报告

A Trial of Oral Glucocorticoids in the Resolution of Recurrent Granulomatous Hypophysitis: A Case Report.

作者信息

Rodriguez-Asuncion Katrina, Crisostomo Thelma

机构信息

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, Makati Medical Center, Philippines.

出版信息

J ASEAN Fed Endocr Soc. 2019;34(2):210-214. doi: 10.15605/jafes.034.02.13. Epub 2019 Nov 9.

DOI:10.15605/jafes.034.02.13
PMID:33442158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7784091/
Abstract

Granulomatous hypophysitis is an extremely rare condition, with no established definitive treatment. An elderly Asian woman was diagnosed to have recurrent granulomatous hypophysitis 5 years after transsphenoidal surgery. No other intervention was done post-operatively. Since another surgery was not advisable due to the high probability of recurrence, she was started on a trial of oral glucocorticoids. After 3 months of steroid therapy, complete resolution of symptoms and sellar mass were achieved.

摘要

肉芽肿性垂体炎是一种极其罕见的疾病,尚无确定的治疗方法。一名老年亚洲女性在经蝶窦手术后5年被诊断为复发性肉芽肿性垂体炎。术后未进行其他干预。由于复发概率高,不建议再次手术,因此开始对她进行口服糖皮质激素试验性治疗。经过3个月的类固醇治疗,症状和蝶鞍肿块完全消退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f469/7784091/dab5334a1855/JAFES-34-2-210-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f469/7784091/76c715c7bdd2/JAFES-34-2-210-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f469/7784091/caf29619f44a/JAFES-34-2-210-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f469/7784091/11dd719862e5/JAFES-34-2-210-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f469/7784091/dab5334a1855/JAFES-34-2-210-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f469/7784091/76c715c7bdd2/JAFES-34-2-210-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f469/7784091/caf29619f44a/JAFES-34-2-210-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f469/7784091/11dd719862e5/JAFES-34-2-210-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f469/7784091/dab5334a1855/JAFES-34-2-210-g004.jpg

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引用本文的文献

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Characteristics of inflammatory and infectious diseases of the pituitary gland in patients undergoing transsphenoidal surgery.经蝶窦手术患者垂体炎性和感染性疾病的特征。
Pituitary. 2023 Aug;26(4):451-460. doi: 10.1007/s11102-023-01333-4. Epub 2023 Jun 30.

本文引用的文献

1
Idiopathic Granulomatous Hypophysitis with Rapid Onset: A Case Report.特发性快速起病的肉芽肿性垂体炎:一例报告
Brain Tumor Res Treat. 2019 Apr;7(1):57-61. doi: 10.14791/btrt.2019.7.e22.
2
Granulomatous hypophysitis: rare disease with challenging diagnosis.肉芽肿性垂体炎:一种诊断具有挑战性的罕见疾病。
Clin Case Rep. 2017 Jun 1;5(7):1147-1151. doi: 10.1002/ccr3.1007. eCollection 2017 Jul.
3
Idiopathic granulomatous hypophysitis: a systematic review of 82 cases in the literature.特发性肉芽肿性垂体炎:文献中82例病例的系统评价
Pituitary. 2014 Aug;17(4):357-65. doi: 10.1007/s11102-013-0510-4.
4
Granulomatous hypophysitis: two case reports and literature review.肉芽肿性垂体炎:两例报告及文献综述
J Zhejiang Univ Sci B. 2009 Jul;10(7):552-8. doi: 10.1631/jzus.B0820355.