马来西亚吉兰丹州哥打巴鲁健康青少年维生素D缺乏症的患病率及危险因素
Prevalence and Risk Factors for Hypovitaminosis D among Healthy Adolescents in Kota Bharu, Kelantan.
作者信息
Hussain Suhaimi, Elnajeh Maged
机构信息
Hospital University Science Malaysia.
出版信息
J ASEAN Fed Endocr Soc. 2020;35(2):176-180. doi: 10.15605/jafes.035.02.05. Epub 2020 Sep 17.
OBJECTIVE
We aim to study the prevalence and risk factors of hypovitaminosis D among healthy adolescents in Kota Bharu, Kelantan based on the most recent Paediatric Consensus guideline.
METHODOLOGY
Ten public schools were selected from Kota Bharu, Kelantan. We analysed their demography (age, gender, ethnicity, income), measured their anthropometry (height, weight, BMI) and finally analysed their vitamin D and intactParathyroid hormone levels.
RESULTS
The prevalence of hypovitaminosis D was 16.9% among healthy teenagers with mean age of 15.9±1.39 years. Multivariate analysis showed female gender (adjusted OR, 95% CI): 23.7 (5.64, 100.3) and Chinese 0.24 (0.07, 0.84) were the significant predictors for hypovitaminosis D.
CONCLUSION
The prevalence of healthy adolescents with hypovitaminosis D in Kota Bharu, Kelantan was 16.9% using the most recent cut off value of 30 nmol/L from the global consensus 2016. Female and Malay were the significant risk factors associated with hypovitaminosis D. Higher cut off value would result in overestimation of prevalence rate of hypovitaminosis D.
目的
根据最新的儿科共识指南，我们旨在研究吉兰丹哥打巴鲁健康青少年维生素D缺乏症的患病率及危险因素。
方法
从吉兰丹哥打巴鲁选取了10所公立学校。我们分析了他们的人口统计学特征（年龄、性别、种族、收入），测量了他们的人体测量学指标（身高、体重、体重指数），最后分析了他们的维生素D和完整甲状旁腺激素水平。
结果
在平均年龄为15.9±1.39岁的健康青少年中，维生素D缺乏症的患病率为16.9%。多变量分析显示，女性（调整后的比值比，95%置信区间）：23.7（5.64，100.3）以及华裔0.24（0.07，0.84）是维生素D缺乏症的显著预测因素。
结论
根据2016年全球共识中最新的30 nmol/L临界值，吉兰丹哥打巴鲁健康青少年维生素D缺乏症的患病率为16.9%。女性和马来族是与维生素D缺乏症相关的显著危险因素。采用更高的临界值会导致维生素D缺乏症患病率的高估。
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