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制定预测老年股骨转子间骨折髓内钉固定术后输血的列线图。

Development of a Nomogram to Predict Postoperative Transfusion in the Elderly After Intramedullary Nail Fixation of Femoral Intertrochanteric Fractures.

机构信息

Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang, People's Republic of China.

Department of Orthopaedics, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang, People's Republic of China.

出版信息

Clin Interv Aging. 2021 Jan 6;16:1-7. doi: 10.2147/CIA.S253193. eCollection 2021.

Abstract

PURPOSE

The aim of our study was to explore the risk factors related to blood transfusion after intramedullary nail fixation of elderly femoral intertrochanteric fracture (FTF) and establish a nomogram prediction model.

PATIENTS AND METHODS

We conducted a retrospective study including elderly FTF patients treated by intramedullary nail between January 2017 and December 2019. Perioperative information was obtained retrospectively, uni- and multivariate regression analyses were performed to determine risk factors for blood transfusion. A nomogram model was established to predict the risk of blood transfusion, and consistency coefficient (C-index) and correction curve were used to evaluate the prediction performance and consistency of the model.

RESULTS

Of 148 patients, 119 were finally enrolled in the study and and 46 patients (38.7%) received a blood transfusion after the operation. Logistic regression analysis the female, lower preoperative Hb, ASA score >2, general anesthesia, and higher intraoperative blood loss were independently associated with the blood transfusion. The accuracy of the contour map for predicting transfusion risk was 0.910.

CONCLUSION

These risk factors are shown on the nomogram and verified. Through the assessment of the risk of blood transfusion and the intervention of modifiable risk factors, we may be able to reduce the blood transfusion rate to a certain extent, so as to further guarantee the safety of the elderly patients during the perioperative period.

摘要

目的

本研究旨在探讨与老年股骨转子间骨折(FTF)髓内钉固定术后输血相关的危险因素,并建立列线图预测模型。

方法

我们进行了一项回顾性研究,纳入了 2017 年 1 月至 2019 年 12 月期间接受髓内钉治疗的老年 FTF 患者。回顾性获取围手术期信息,进行单因素和多因素回归分析,确定输血的危险因素。建立列线图模型预测输血风险,并使用一致性系数(C 指数)和校正曲线评估模型的预测性能和一致性。

结果

在 148 例患者中,最终有 119 例患者纳入研究,其中 46 例(38.7%)患者术后接受输血。Logistic 回归分析显示,女性、术前 Hb 较低、ASA 评分>2、全身麻醉和术中出血量较高与输血独立相关。输血风险预测轮廓图的准确性为 0.910。

结论

这些危险因素在列线图上得到了体现和验证。通过评估输血风险和干预可改变的危险因素,我们或许可以在一定程度上降低输血率,从而进一步保障老年患者围手术期的安全。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4614/7797293/de798c9ec8b6/CIA-16-1-g0001.jpg

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