Biot Nicolas, Romito Deborah, Bonifazi Davide
School of Chemistry, Cardiff University, Park Place, CF10 3AT, Cardiff, United Kingdom.
Institute of Organic Chemistry, University of Vienna, 1090 Vienna, Austria.
Cryst Growth Des. 2021 Jan 6;21(1):536-543. doi: 10.1021/acs.cgd.0c01318. Epub 2020 Dec 3.
In this work, we design and synthesize supramolecular 2,5-substituted chalcogenazolo[5,4-β]pyridine (CGP) synthons arranging in supramolecular ribbons at the solid state. A careful choice of the combination of substituents at the 2- and 5-positions on the CGP scaffold is outlined to accomplish supramolecular materials by means of multiple hybrid interactions, comprising both chalcogen and hydrogen bonds. Depending on the steric and electronic properties of the substituents, different solid-state arrangements have been achieved. Among the different moieties on the 5-position, an oxazole unit has been incorporated on the Se- and Te-congeners by Pd-catalyzed cross-coupling reaction and a supramolecular ribbon-like organization was consistently obtained at the solid state.
在这项工作中，我们设计并合成了超分子2,5-取代硫族氮杂并[5,4-β]吡啶（CGP）合成子，其在固态下排列成超分子带。概述了对CGP支架上2位和5位取代基组合的精心选择，以通过包括硫族键和氢键在内的多种杂化相互作用来实现超分子材料。根据取代基的空间和电子性质，已实现了不同的固态排列。在5位的不同部分中，通过钯催化的交叉偶联反应将恶唑单元引入到硒和碲的同系物中，并在固态下始终获得超分子带状结构。
