Matthews K A, Stoney C M
Department of Psychiatry, University of Pittsburgh School of Medicine, PA 15213.
Psychosom Med. 1988 Jan-Feb;50(1):46-56. doi: 10.1097/00006842-198801000-00006.
The present investigation examined the influence of sex and age on blood pressure and heart rate responses in 125 women, 93 men, 121 girls, and 96 boys to three standardized stressors: serial subtraction, mirror-image tracing, and isometric handgrip. With baseline measures and body mass index controlled for, analyses of covariance showed that adults had greater systolic blood pressure responses than did children; men had greater blood pressure responses to all stressors than did women; and high school boys had greater systolic blood pressure responses than did high school girls. In addition, adults had smaller heart rate responses during isometric handgrip than did children, and high school students had smaller heart rate responses during all tasks than did the remaining, younger students. These results show that sex and age are important determinants of the magnitude of cardiovascular adjustments during stressors. The implications of these results are discussed in light of sex differences in coronary heart disease morbidity and mortality.
本研究调查了125名女性、93名男性、121名女孩和96名男孩的性别与年龄对血压和心率的影响,这些被试者需对三种标准化应激源做出反应:连续减法运算、镜像追踪和等长握力运动。在控制了基线测量值和体重指数后,协方差分析表明,成年人的收缩压反应比儿童更大;男性对所有应激源的血压反应比女性更大;高中男生的收缩压反应比高中女生更大。此外,成年人在进行等长握力运动时的心率反应比儿童小,高中生在所有任务中的心率反应比其他年龄更小的学生小。这些结果表明,性别和年龄是应激源期间心血管调节幅度的重要决定因素。根据冠心病发病率和死亡率的性别差异,对这些结果的意义进行了讨论。