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作者信息

Nguyen Aude, Posfay-Barbe Klara, Blanchard-Rohner Géraldine, Buvelot Hélène, Eberhardt Christiane, Huttner Benedikt, Negro Francesco, Pham Truong-Thanh, Schibler Manuel, Vetter Pauline, Wagner Noémie, Zanella Marie-Céline, Jacquérioz Frédérique, Huttner Angela

机构信息

Service des maladies infectieuses, Département de médecine, HUG, 1211 Genève 14.

Unité d'infectiologie pédiatrique, Service de pédiatrie générale, Département de la femme, de l'enfant et de l'adolescent, HUG, 1211 Genève 14.

出版信息

Rev Med Suisse. 2021 Jan 13;17(720-1):42-49.

PMID:33443830

Abstract

What's new in infectious diseases in 2020 ? This year has been marked by the COVID-19 pandemic, prompting a review of the current knowledge on SARS-CoV-2 and its management in this article. The results of the Swiss project « PIRATE » indicate non-inferiority between CRP-guided antibiotic durations or fixed 7-day durations and 14-day durations for Gram-negative bacteremia. A Mongolian study did not show any benefit of vitamin D substitution in protecting children from tuberculosis. Baloxavir, a new antiviral against the flu, has been approved by Swissmedic. Finally, new American recommendations for therapeutic monitoring of vancomycin and universal screening for hepatitis C virus have been published.

摘要

2020年传染病领域有哪些新进展？今年以新冠疫情为标志，促使本文对当前关于严重急性呼吸综合征冠状病毒2（SARS-CoV-2）及其治疗的知识进行回顾。瑞士“PIRATE”项目的结果表明，对于革兰氏阴性菌血症，在降钙素原（CRP）指导的抗生素使用疗程或固定7天疗程与14天疗程之间不存在非劣效性。一项蒙古的研究未显示维生素D替代疗法在保护儿童预防结核病方面有任何益处。一种新型抗流感病毒药物巴洛沙韦已获瑞士药品监管局批准。最后，美国发布了关于万古霉素治疗监测和丙型肝炎病毒普遍筛查的新建议。