Inagawa T, Ishikawa S, Aoki H, Takahashi M, Yoshimoto H
Department of Neurosurgery, Shimane Prefectural Central Hospital, Japan.
Stroke. 1988 Feb;19(2):170-5. doi: 10.1161/01.str.19.2.170.
During the 5-year period from 1980 to 1984, the incidence of subarachnoid hemorrhage due only to rupture of aneurysms was investigated in Izumo City, a small city with a population of 79,026. Additionally, to ascertain the relation of incidence to the size of the geographic area and/or population, a similar analysis was made on a larger area of Shimane Prefecture, including Izumo City, with a total population of 789,712. During this 5-year period, a total of 83 patients with aneurysmal subarachnoid hemorrhage were hospitalized in Izumo City, 548 patients in Shimane Prefecture. Ruptured aneurysms were confirmed in 77 cases (93%) in Izumo City and 466 cases (85%) in Shimane Prefecture. The crude annual incidences of aneurysmal subarachnoid hemorrhage for Izumo City and Shimane Prefecture were 21.0 and 13.9 per 100,000 population for all ages, and the age-adjusted annual incidences (adjusted to the 1980 population of Japan) were 18.3 and 11.0 per 100,000 for all ages, respectively. For both Izumo City and Shimane Prefecture, the age-specific annual incidences peaked at the ages of 50-69 years, and the highest incidence was 92.3 per 100,000 men from Izumo City in the eighth decade of life. The annual incidence of subarachnoid hemorrhage for Izumo City is the highest reported to date. If a wider area, such as Shimane Prefecture, were studied many patients in poor condition, particularly elderly patients, would be missed. To determine accurately the incidence of aneurysmal subarachnoid hemorrhage, it thus might be better to conduct the study in a small city such as Izumo City.
在1980年至1984年的5年期间，对出云市（一个人口为79,026的小城市）仅因动脉瘤破裂导致的蛛网膜下腔出血发病率进行了调查。此外，为确定发病率与地理区域大小和/或人口的关系，对包括出云市在内的岛根县更大区域进行了类似分析，该区域总人口为789,712。在这5年期间，出云市共有83例动脉瘤性蛛网膜下腔出血患者住院，岛根县有548例。出云市77例（93%）、岛根县466例（85%）确诊为动脉瘤破裂。出云市和岛根县动脉瘤性蛛网膜下腔出血的粗年发病率在各年龄段均为每10万人口21.0例和13.9例，年龄调整后的年发病率（根据1980年日本人口调整）在各年龄段分别为每10万人口18.3例和11.0例。出云市和岛根县的年龄别年发病率均在50 - 69岁达到峰值，最高发病率是出云市80岁男性每10万人口92.3例。出云市蛛网膜下腔出血的年发病率是迄今为止报告的最高值。如果研究更广泛的区域，如岛根县，许多病情不佳的患者，尤其是老年患者将会被遗漏。因此，为准确确定动脉瘤性蛛网膜下腔出血的发病率，在出云市这样的小城市开展研究可能更好。
