Yonas H, Gur D, Claassen D, Wolfson S K, Moossy J
Department of Neurosurgery, University of Pittsburgh, Pennsylvania.
Stroke. 1988 Feb;19(2):228-38. doi: 10.1161/01.str.19.2.228.
When the lateral striate arteries of baboons are occluded, an immediate cessation of blood flow followed by a transient, minimal restitution of flow occurs in that vascular distribution. These findings are evident from serial xenon/computed tomography cerebral blood flow imaging. In our study, infarction consistently accompanied arterial occlusion for 6 hours or more. The xenon/computed tomography method provides a sensitive, noninvasive technique for examining sequential alterations of cerebral blood flow in small regions deep within the brain. This methodology for recording cerebral blood flow permits correlative studies of cerebral infarction, clinically and experimentally, and allows reasonable inferences about the probabilities of neural tissue damage.
当狒狒的外侧纹状体动脉被阻塞时，在该血管分布区域会立即出现血流停止，随后血流出现短暂的、最小程度的恢复。这些发现通过系列氙/计算机断层扫描脑血流成像得以明确。在我们的研究中，梗死始终伴随动脉阻塞6小时或更长时间。氙/计算机断层扫描方法为检查脑深部小区域脑血流的连续变化提供了一种灵敏的、非侵入性技术。这种记录脑血流的方法允许在临床和实验上对脑梗死进行相关性研究，并能对神经组织损伤的可能性做出合理推断。
