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DnaJ蛋白调控拟南芥茎尖分生组织中的基因表达。

DnaJ Proteins Regulate Expression in Shoot Apical Meristem of Arabidopsis.

作者信息

Jia Tianqi, Li Fan, Liu Shuang, Dou Jin, Huang Tao

机构信息

School of Life Sciences, Xiamen University, Xiamen 361102, China.

出版信息

Plants (Basel). 2021 Jan 12;10(1):136. doi: 10.3390/plants10010136.

DOI:10.3390/plants10010136
PMID:33445404
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7827474/
Abstract

WUSCHEL (WUS) protein regulates stem cell function in shoot apical meristem of . The expression of gene is strictly regulated by developmental cues and environmental factors. As DnaJ domain-containing proteins, SDJ1 and SDJ3 have been proven to play an important role in transcriptional activation of promoter methylated genes. Here, we showed that three DnaJ domain-containing proteins including SDJ1 and SDJ3 can bind WUS protein as a complex, which further maintain the expression of gene by binding to promoter. We propose a model how DnaJ domain-containing proteins are involved in the self-regulation of gene in stem cells maintenance of Arabidopsis.

摘要

WUSCHEL(WUS)蛋白调控拟南芥茎尖分生组织中的干细胞功能。该基因的表达受到发育线索和环境因素的严格调控。作为含DnaJ结构域的蛋白,SDJ1和SDJ3已被证明在启动子甲基化基因的转录激活中发挥重要作用。在此,我们表明包括SDJ1和SDJ3在内的三种含DnaJ结构域的蛋白可以作为一个复合体与WUS蛋白结合,进而通过与该基因启动子结合来维持其表达。我们提出了一个关于含DnaJ结构域的蛋白如何参与拟南芥干细胞维持过程中该基因自我调控的模型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/0eea29ad0529/plants-10-00136-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/a79df6a7c5d9/plants-10-00136-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/348c3f6c45bc/plants-10-00136-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/e21e042cf9e0/plants-10-00136-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/5a1e87c97ed5/plants-10-00136-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/b091a70537a6/plants-10-00136-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/fefe6358e9a9/plants-10-00136-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/0eea29ad0529/plants-10-00136-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/a79df6a7c5d9/plants-10-00136-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/348c3f6c45bc/plants-10-00136-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/e21e042cf9e0/plants-10-00136-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/5a1e87c97ed5/plants-10-00136-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/b091a70537a6/plants-10-00136-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/fefe6358e9a9/plants-10-00136-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf85/7827474/0eea29ad0529/plants-10-00136-g007.jpg

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本文引用的文献

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J Integr Plant Biol. 2019 Feb;61(2):120-139. doi: 10.1111/jipb.12767.
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A DNA methylation reader complex that enhances gene transcription.一种增强基因转录的 DNA 甲基化读码器复合物。
Science. 2018 Dec 7;362(6419):1182-1186. doi: 10.1126/science.aar7854.
3
Novel DNAJ-related proteins in Arabidopsis thaliana.拟南芥中新型 DNAJ 相关蛋白。
肽酶 DA1 切割并破坏 WUSCHEL 以控制茎尖分生组织的大小。
Nat Commun. 2024 May 31;15(1):4627. doi: 10.1038/s41467-024-48361-7.
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Transcriptomic analysis to reveal the differentially expressed miRNA targets and their miRNAs in response to Ralstonia solanacearum in ginger species.转录组分析揭示了生姜物种对青枯菌响应的差异表达 miRNA 靶标及其 miRNA。
BMC Plant Biol. 2021 Jul 29;21(1):355. doi: 10.1186/s12870-021-03108-0.
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