Berry A D, Kepes J J, Wetzel M D
Department of Pathology and Oncology, University of Kansas, College of Health Sciences and Hospital, Kansas City 66103.
Stroke. 1988 Feb;19(2):256-60. doi: 10.1161/01.str.19.2.256.
Duplication or fenestration of the basilar artery, a result of an embryologic malformation, has an incidence of up to 5.3% in the general population. The most common complication of this anomaly is the formation of aneurysms. Thrombosis of a partially duplicated basilar artery developed in a 43-year-old man who complained of visual disturbances followed by seizures and coma, and who eventually died. Autopsy showed a partially organized thrombus occluding both halves of a duplicated portion of the basilar artery, old infarcts in the calcarine cortices, and a recent large infarct in the basis pontis. There was only minimal atherosclerosis of other intracranial arteries, including the vertebral arteries. Hemodynamic disturbances and turbulent blood flow at the site of fenestration may be the cause of the thrombosis that occurred in this artery.
基底动脉重复或开窗是一种胚胎发育畸形的结果，在普通人群中的发生率高达5.3%。这种异常最常见的并发症是动脉瘤形成。一名43岁男性出现基底动脉部分重复血栓形成，该患者先是主诉视觉障碍，随后出现癫痫发作和昏迷，最终死亡。尸检显示，部分机化的血栓阻塞了基底动脉重复部分的两半，距状皮质有陈旧性梗死灶，脑桥基底部有近期的大面积梗死灶。其他颅内动脉，包括椎动脉，仅有轻微动脉粥样硬化。开窗部位的血流动力学紊乱和血流湍急可能是该动脉发生血栓形成的原因。
