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立体定向体部放疗(SBRT)治疗心肌转移瘤 1 例报告

Stereotactic Body Radiation Therapy (SBRT) for a Patient with a Myocardial Metastasis: A Case Report.

机构信息

Juravinski Cancer Centre, Hamilton, ON L8V 5C2, Canada.

Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.

出版信息

Curr Oncol. 2021 Jan 12;28(1):390-395. doi: 10.3390/curroncol28010041.

Abstract

Metastatic lesions of the heart are rare but have the potential to cause significant morbidity. We describe the case of a patient with renal cell carcinoma who presented with shortness of breath and palpitations and was found to have a metastatic myocardial lesion causing arrythmia. He received stereotactic body radiation therapy (SBRT) to alleviate symptoms and provide local control. SBRT planning was executed using a four-dimensional computed tomography (4DCT) scan to account for respiratory and cardiac motion. Images from a planning magnetic resonance imaging (MRI) scan and a gated diagnostic MRI scan of the heart were fused with the 4DCT to assist with delineating the tumour. A dose of 30 Gy in five fractions was delivered without incident. The patient's cardiac MRI at two months post-treatment showed stability of his cardiac lesion. He subsequently died of distant disease progression, without any recurrence of his cardiac symptoms. SBRT may be considered for patients who present with a symptomatic metastatic cardiac lesion.

摘要

心脏转移瘤较为罕见,但有可能导致严重的发病率。我们描述了一例患有肾细胞癌的患者,该患者出现呼吸急促和心悸,并被发现存在导致心律失常的转移性心肌病变。他接受了立体定向体部放射治疗(SBRT)以缓解症状并提供局部控制。SBRT 计划使用四维计算机断层扫描(4DCT)来考虑呼吸和心脏运动。来自计划磁共振成像(MRI)扫描和心脏门控诊断 MRI 扫描的图像与 4DCT 融合以协助描绘肿瘤。以 30Gy 的剂量分 5 次给予,没有发生意外。患者治疗后两个月的心脏 MRI 显示其心脏病变稳定。随后,他因远处疾病进展而死亡,没有出现心脏症状的复发。对于出现有症状的转移性心脏病变的患者,可以考虑 SBRT。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db3d/7903268/e21f177f2d03/curroncol-28-00041-g001.jpg

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