Royce P L, Zimmern P E, deKernion J B
Department of Surgery, UCLA School of Medicine.
Urol Res. 1988;16(1):37-41. doi: 10.1007/BF00264626.
Lyophilized dura mater (Lyodura) and autogenous free peritoneum were compared in the replacement of the partially resected renal pelvis and uretero-pelvic junction (UPJ) in the pig. The Lyodura and peritoneum grafts were both progressively resorbed, and replaced by fibroblasts which formed a mature scar lined by transitional epithelium, but without smooth muscle regeneration. Lyodura was found to be superior to free peritoneum with a longer time before resorption of the graft, less intense inflammatory reaction, absence of metaplastic bone formation, less risk of urine leak and greater ease of surgical manipulation.
在猪身上，对冻干硬脑膜（Lyodura）和自体游离腹膜在部分切除肾盂和输尿管肾盂连接部（UPJ）替代方面进行了比较。Lyodura和腹膜移植物均逐渐被吸收，并被成纤维细胞替代，这些成纤维细胞形成了由移行上皮衬里的成熟瘢痕，但无平滑肌再生。结果发现，Lyodura优于游离腹膜，其移植物吸收前的时间更长，炎症反应较轻，无化生骨形成，尿漏风险较小，手术操作更简便。
