Hutschenreiter G, Rumpelt H J, Klippel K F, Hohenfellner R
Invest Urol. 1978 Mar;15(5):375-9.
In 13 rabbits the fundus of the bladder was resected and the defect repaired by a free peritoneal transplant from the lateral abdominal wall. One animal died postoperatively of purulent peritonitis. In the remaining animals the transplant healed with no signs of irritation. The mean reduction of bladder capacity per body weight between the 5th and 18th postoperative week was only 13 per cent. Histologic tests after 5 weeks showed a germinating epithelium on the transplant which was replaced by a fibromuscular lamina after 10 weeks. The successful results of these animal experiments seem to justify the clinical use of free peritoneal transplants. The good healing tendency and matrix function of this tissue permit transplantation of the peritoneum wherever intraoperative defects occur or suture dehiscence may be expected.
在13只兔子身上，切除膀胱底部，并通过取自侧腹壁的游离腹膜移植来修复缺损。1只动物术后死于化脓性腹膜炎。其余动物的移植组织愈合良好，无刺激迹象。术后第5周和第18周之间，膀胱容量相对于体重的平均减少量仅为13%。5周后的组织学检查显示移植组织上有上皮细胞生长，10周后被纤维肌层取代。这些动物实验的成功结果似乎证明了游离腹膜移植在临床上的应用是合理的。这种组织良好的愈合倾向和基质功能使得在术中出现缺损或可能预期缝线裂开的任何地方都可以进行腹膜移植。
