Hino Yumika, Eshima Nobuoki, Bacal Kira, Tokumaru Osamu
Kotake Municipal Hospital, 1191 Katsuno, Kotake-machi, Kurate District, Fukuoka 820-1103, Japan.
Center for Educational Outreach and Admissions, Kyoto University, Yoshida-honmachi, Sakyo-ku, Kyoto 606-8501, Japan.
Children (Basel). 2021 Jan 12;8(1):40. doi: 10.3390/children8010040.
Sexually transmitted diseases (STDs) are causes of public health burden globally. The purpose of this study is to document age-specific and sex-related changes in the morbidity of four representative STDs in children. Japanese national surveillance data from 1999 to 2017 on morbidities of the following four STDs were analyzed by age and sex: (NG), (CT), condylomata acuminate (CA), and genital herpes simplex virus (GHSV). The morbidities of males and females in each age group were compared through the male-to-female morbidity (MFM) ratios. The MFM ratios were not different from one in infants, less than one in children, and greater than one after puberty in all four STDs. The reversal of MFM ratio less than 1 to greater than 1 for NG infection was observed between 10-14 and 15-19 year of age, i.e., during the puberty, while that for GHSV infection was observed between 35-39 and 40-44 year of age, i.e., during adulthood. In conclusion, the morbidities of the four STDs were similar between the sexes in infants, and were higher in female children than in male children, while the morbidities in all four diseases were higher in men after puberty.
性传播疾病（STDs）是全球公共卫生负担的成因。本研究的目的是记录儿童中四种代表性性传播疾病发病率的年龄特异性和性别相关变化。分析了日本1999年至2017年关于以下四种性传播疾病发病率的全国监测数据，按年龄和性别分类：淋病（NG）、沙眼衣原体（CT）、尖锐湿疣（CA）和单纯疱疹病毒（GHSV）。通过男女性发病率（MFM）比率比较了各年龄组男性和女性的发病率。在所有四种性传播疾病中，婴儿的MFM比率与1无差异，儿童的MFM比率小于1，青春期后的MFM比率大于1。淋病感染的MFM比率在10 - 14岁和15 - 19岁之间，即青春期期间，从小于1反转至大于1，而单纯疱疹病毒感染的MFM比率在35 - 39岁和40 - 44岁之间，即成年期期间出现反转。总之，这四种性传播疾病的发病率在婴儿期男女相似，女童高于男童，而青春期后所有四种疾病的发病率男性均高于女性。
