Department of Advanced General Dentistry, Faculty of Dentistry, Mahidol University, Bangkok, 10400, Thailand.
Department of Pharmacology, Faculty of Science, Mahidol University, 272 Rama VI Road, Ratchathewi, Bangkok, 10400, Thailand.
Sci Rep. 2021 Jan 14;11(1):1384. doi: 10.1038/s41598-020-80910-0.
Coffee beverage consumption is well-known to exert various health benefits; however, the effects of coffee aroma are rarely explored. This study aimed to investigate the calming effect of inhaling coffee aroma while the patients underwent dental procedures (probing and scaling). Salivary α-amylase (sAA) and cortisol (sCort) levels were measured as proxies of sympathetic nervous system and hypothalamic-pituitary-adrenal axis responses to stress respectively. Blood pressures and pulse rates were recorded. The results showed that undergoing dental procedures could increase sAA and sCort levels of the patients inhaling sham aroma while those inhaling coffee aroma had significantly decreased sAA and sCort levels (40% and 25% differences, respectively). The pulse rates of those inhaling coffee aroma were also lower. Subjective assessment using visual analog scale was in line with objective measures as well. The preference for coffee aroma or the frequency of coffee drinking had no effect on the sAA and sCort responses. This is the first study to provide evidence on the effect of coffee aroma on sAA and sCort levels in patients undergoing dental procedures.
咖啡饮品的消费被广泛认为对健康有多种益处；然而，咖啡香气的影响却很少被探讨。本研究旨在调查在患者接受牙科治疗（探查和洁治）时吸入咖啡香气的镇静效果。唾液 α-淀粉酶（sAA）和皮质醇（sCort）水平被用作交感神经系统和下丘脑-垂体-肾上腺轴对应激反应的替代指标进行测量。血压和脉搏率也被记录下来。结果表明，接受牙科治疗会增加吸入伪香气的患者的 sAA 和 sCort 水平，而吸入咖啡香气的患者的 sAA 和 sCort 水平则显著降低（分别降低了 40%和 25%）。吸入咖啡香气的患者的脉搏率也较低。使用视觉模拟量表进行的主观评估与客观测量结果一致。对咖啡香气的偏好或喝咖啡的频率对 sAA 和 sCort 反应没有影响。这是第一项研究，提供了咖啡香气对接受牙科治疗的患者的 sAA 和 sCort 水平的影响的证据。
