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急性A型主动脉夹层全主动脉弓置换术后体温过低——术后体温过低发生的多因素分析及风险识别

Postoperative hypothermia after total aortic arch replacement in acute type A aortic dissection-multivariate analysis and risk identification for postoperative hypothermia occurrence.

作者信息

Liu Huan, Wang Xiuwen, Liu Shun, Cong Shuo, Lu Yuntao, Yang Ye, Wang Wenshuo, Lai Hao, Li Xin, Wei Lai, Wang Chunsheng

机构信息

Department of Cardiovascular Surgery, Zhongshan Hospital, Shanghai Cardiovascular Institution, Fudan University, Shanghai, China.

Department of Intensive Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.

出版信息

J Thorac Dis. 2020 Dec;12(12):7089-7096. doi: 10.21037/jtd-20-1709.

Abstract

BACKGROUND

Postoperative hypothermia (PH) is a common physiological abnormality associated with increased morbidity and mortality after non-cardiac surgery. The incidence, risk factors of PH and its impact on early outcomes after total aortic arch replacement are not clear.

METHODS

We conducted a retrospective cohort study in patients with acute type A aortic dissection who underwent total arch replacement from January 2013 to December 2016 at our institution. Basic variables, procedural and postoperative early outcomes were collected. Univariate and multivariate statistical analysis were performed for statistical interpretation. The early outcomes were compared between patients with or without PH.

RESULTS

A total of 300 patients (age 53.8±11.5 years, female 63, 21.0%) with acute type A aortic dissection underwent total arch replacement. Forty-four patients (14.7%) developed PH. The independent risk factors of PH are age and the intraoperative lowest bladder temperature. There is no significant difference in major postoperative morbidity and mortality between patients with or without PH.

CONCLUSIONS

The incidence of PH after total arch replacement in acute type A aortic dissection is relatively low. The independent risk factors of PH in this population include age and the intraoperative lowest bladder temperature. With comprehensive rewarming strategy upon arrival at the ICU, the PH is easy to be corrected, and the adverse effect of transient PH on early outcomes after arch surgery is minimal.

摘要

背景

术后低体温(PH)是一种常见的生理异常,与非心脏手术后发病率和死亡率增加相关。全主动脉弓置换术后PH的发生率、危险因素及其对早期结局的影响尚不清楚。

方法

我们对2013年1月至2016年12月在我院接受全弓置换的急性A型主动脉夹层患者进行了一项回顾性队列研究。收集基本变量、手术和术后早期结局。进行单因素和多因素统计分析以进行统计学解释。比较有或无PH患者的早期结局。

结果

共有300例急性A型主动脉夹层患者(年龄53.8±11.5岁,女性63例,占21.0%)接受了全弓置换。44例患者(14.7%)发生了PH。PH的独立危险因素是年龄和术中最低膀胱温度。有或无PH患者术后主要发病率和死亡率无显著差异。

结论

急性A型主动脉夹层全弓置换术后PH的发生率相对较低。该人群中PH的独立危险因素包括年龄和术中最低膀胱温度。在进入重症监护病房后采用综合复温策略,PH易于纠正,短暂性PH对弓部手术后早期结局的不良影响最小。

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Consequences of perioperative hypothermia.围手术期体温过低的后果。
Handb Clin Neurol. 2018;157:687-697. doi: 10.1016/B978-0-444-64074-1.00041-0.
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The Significance of Hypothermia in Abdominal Aortic Aneurysm Repair.低温在腹主动脉瘤修复中的意义。
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