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主动脉弓几何形态变化与斯坦福B型主动脉夹层的风险

Changes in aortic arch geometry and the risk for Stanford B dissection.

作者信息

Qiu Peng, Liu Junchao, Chen Yuqian, Zha Binshan, Ye Kaichuang, Qin Jinbao, Hao Peipei, Kang Jiwen, Zhang Chao, Zhu Huagang, Lu Xinwu

机构信息

Department of Vascular Surgery, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

School of Public Economics and Administration, Shanghai University of Finance and Economics, Shanghai, China.

出版信息

J Thorac Dis. 2020 Dec;12(12):7193-7201. doi: 10.21037/jtd-20-1643.

Abstract

BACKGROUND

The increase in aortic diameter is not closely associated with type B aortic dissection (TBAD); morphological risk factors other than aortic diameter may help to better identify patients at risk for TBAD. The purpose of this study was to investigate possible morphological factors associated with the occurrence of TBAD.

METHODS

This study was a retrospective, multicenter, cross-sectional study. We collected 94 patients with TBAD as the TBAD group and 534 patients with healthy aortas as the healthy control group. Morphometric data were collected on three-dimensional models of the thoracic aorta. A propensity score matching (PSM) analysis was conducted to reduce the potential for confounding by baseline factors.

RESULTS

The number of patients in the TBAD group was 75 after PSM. Longer lengths of the aortic arch (28.00±7.42 25.14±7.11 cm) were observed in patients with TBAD. The width (80.04±17.27 71.73±15.55 mm) and height (24.92±11.39 19.37±10.10 mm) of the aortic arch in patients with TBAD were both larger than those of healthy controls. The morphological changes associated with the occurrence of type B acute dissection were most pronounced in the geometry of the aortic arch.

CONCLUSIONS

This study demonstrates that TBAD was associated with longer lengths of aortic arch and with larger arch height and width.

摘要

背景

主动脉直径的增加与B型主动脉夹层(TBAD)并无密切关联;除主动脉直径外的形态学危险因素可能有助于更好地识别TBAD的高危患者。本研究旨在探讨与TBAD发生相关的可能形态学因素。

方法

本研究为一项回顾性、多中心横断面研究。我们收集了94例TBAD患者作为TBAD组,以及534例主动脉健康的患者作为健康对照组。在胸主动脉的三维模型上收集形态学数据。进行倾向评分匹配(PSM)分析以降低基线因素造成混杂的可能性。

结果

PSM后TBAD组患者数量为75例。TBAD患者的主动脉弓长度更长(28.00±7.42对25.14±7.11cm)。TBAD患者的主动脉弓宽度(80.04±17.27对71.73±15.55mm)和高度(24.92±11.39对19.37±10.10mm)均大于健康对照组。与B型急性夹层发生相关的形态学变化在主动脉弓的几何形态中最为明显。

结论

本研究表明,TBAD与主动脉弓长度较长以及弓高度和宽度较大有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66ca/7797824/23f759c532bc/jtd-12-12-7193-f1.jpg

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