Klimko Artsiom, Dandes Mariana, Paslaru Francesca, Giovani Andrei
Division of Physiology and Neuroscience, University of Medicine and Pharmacy "Carol Davila", Bucharest, ROU.
Department of Neurological Surgery, Emergency Clinical Hospital "Arseni-Bagdasar", Bucharest, ROU.
Cureus. 2020 Dec 13;12(12):e12060. doi: 10.7759/cureus.12060.
Anaplastic ganglioglioma (AGG) is a rare and aggressive counterpart of the more benign and frequently encountered glioma. Herein, we present a 21-year-old female who presented with episodes of total amnesia and complex partial seizures, which led to the diagnosis of AGG localized to the medial temporal lobe. She subsequently underwent surgical cytoreduction of the tumor three times with adjuvant chemoradiotherapy. The extent of resection throughout the surgeries was hindered by the extension of the tumor to critical neurovascular structures; during the last surgery, invasion into the pons was noted, which posed a significant clinical challenge.
间变性节细胞胶质瘤（AGG）是一种罕见且侵袭性强的肿瘤，与之相对的是更良性且常见的胶质瘤。在此，我们报告一名21岁女性，她出现了完全性遗忘发作和复杂部分性癫痫，最终诊断为局限于颞叶内侧的AGG。她随后接受了三次肿瘤手术减瘤，并辅以放化疗。由于肿瘤侵犯关键神经血管结构，手术切除范围受到限制；在最后一次手术中，发现肿瘤侵犯脑桥，这带来了重大的临床挑战。
