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甲状腺脓肿——两例病例报告

thyroid abscess-two case reports.

作者信息

Khoo Kah Seng, Koh Peng Soon, Ng Khoon Leong

机构信息

Surgical Resident, Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

General & Hepato-biliary Surgeon, Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

出版信息

Gland Surg. 2020 Dec;9(6):2198-2203. doi: 10.21037/gs-20-474.

Abstract

Acute suppurative thyroiditis account for <1% of thyroid diseases and is uncommon because of the gland's encapsulation, iodine-rich environment, good vascular supply and extensive lymphatic drainage. It has been reported in patients with underlying goiters, thyroid cancers and in immuno-compromised patients. The usual causative organisms are and . Rarer organisms include . and . Due to its rarity (as there have been only 28 cases of thyroid abscess being reported in the literature till 2020), only case reports are available to guide management. We report two cases of thyroid abscess due to in our institution that may herald the re-emergence of this uncommon infection of the thyroid gland and to raise awareness for all clinicians. Both patients presented with neck swelling, dysphagia and sepsis. Surgical intervention was warranted in both patients due to the severity of the disease and failed medical therapy. Recovery was uneventful following adequate surgical intervention and antibiotic therapy according to the culture and sensitivity report of the pathogen. This case report highlights that both patients were immunocompromised, and they contracted thyroid abscess without any gastrointestinal involvement. Thus, a high index of suspicion for thyroid abscess in immunocompromised patients can expedite the diagnosis and appropriate management can be commenced such as antibiotic therapy, percutaneous aspiration and surgical drainage in the event of failed medical therapy.

摘要

急性化脓性甲状腺炎占甲状腺疾病的比例不到1%,由于甲状腺有包膜、富含碘的环境、良好的血液供应和广泛的淋巴引流,所以这种疾病并不常见。据报道,患有潜在甲状腺肿、甲状腺癌的患者以及免疫功能低下的患者会出现这种疾病。常见的致病微生物是……和……。罕见的微生物包括……和……。由于其罕见性(截至2020年,文献中仅报道了28例甲状腺脓肿病例),目前仅有病例报告可用于指导治疗。我们报告了我院两例由……引起的甲状腺脓肿病例,这可能预示着这种罕见的甲状腺感染再次出现,并提高所有临床医生的认识。两名患者均出现颈部肿胀、吞咽困难和败血症。由于病情严重且药物治疗无效,两名患者均需要进行手术干预。根据病原体的培养和药敏报告,在进行充分的手术干预和抗生素治疗后,患者恢复顺利。本病例报告强调,两名患者均免疫功能低下,他们感染了……甲状腺脓肿,且无任何胃肠道受累情况。因此,对免疫功能低下患者高度怀疑……甲状腺脓肿可加快诊断,并可开始适当的治疗,如抗生素治疗、经皮穿刺抽吸,以及在药物治疗无效时进行手术引流。

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本文引用的文献

3
5
Thyroid Abscess: Challenges in Diagnosis and Management.甲状腺脓肿:诊断与治疗中的挑战
J Investig Med High Impact Case Rep. 2018 May 25;6:2324709618778709. doi: 10.1177/2324709618778709. eCollection 2018 Jan-Dec.
6
CARE guidelines for case reports: explanation and elaboration document.病例报告的CARE指南:解释与阐述文件。
J Clin Epidemiol. 2017 Sep;89:218-235. doi: 10.1016/j.jclinepi.2017.04.026. Epub 2017 May 18.
7
Idiopathic thyroid abscess.特发性甲状腺脓肿
Int J Surg Case Rep. 2014;5(8):484-6. doi: 10.1016/j.ijscr.2014.05.019. Epub 2014 Jun 10.
9
A pain in the neck: thyroid abscess.令人头疼的问题:甲状腺脓肿
Am J Med. 2014 Mar;127(3):e5-6. doi: 10.1016/j.amjmed.2013.09.036. Epub 2013 Oct 29.
10
Acute tuberculous abscess of the thyroid gland.甲状腺急性结核性脓肿
BMJ Case Rep. 2012 Sep 25;2012:bcr2012006906. doi: 10.1136/bcr-2012-006906.

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