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成人阑尾炎的非手术抗生素治疗:对临床活跃外科医生的一项调查

Nonoperative Antibiotic Treatment of Appendicitis in Adults: A Survey among Clinically Active Surgeons.

作者信息

Reinisch Alexander, Reichert Martin, Hecker Andreas, Padberg Winfried, Ulrich Frank, Liese Juliane

机构信息

Department of General, Visceral and Oncologic Surgery, Hospital and Clinics Wetzlar, Wetzlar, Germany.

Department of General, Visceral, Thoracic, Transplant and Pediatric Surgery, University Hospital of Giessen, Giessen, Germany.

出版信息

Visc Med. 2020 Dec;36(6):494-500. doi: 10.1159/000506058. Epub 2020 Feb 11.

Abstract

BACKGROUND

As a result of well-publicized studies, the nonsurgical antibiotic therapy of uncomplicated acute appendicitis has been propagated since 2006. A final assessment regarding efficiency and long-term results is not possible; however, nonoperative therapy of acute appendicitis is actually being discussed more diversely and receives a lot of attention. It is still unknown how far this therapy has found its way into everyday clinical care.

METHODS

An online questionnaire was sent to 1,400 randomly selected specialists for general/visceral surgery in Germany. Representativeness was achieved by a preselection according to the geographical origin and the care level of the hospitals.

RESULTS

14% of surgeons stated that they methodically treat appendicitis conservatively. 38.1% do so in exceptional cases, while 48.8% reject this therapy. For methodically use, sonography or computed tomography is demanded beforehand. Nonoperative therapy is performed more often in metropolitan areas and maximum-care/university hospitals. Patients' request for antibiotic therapy is an important factor for conservative treatment. The main argument against this therapy is "medical doubts." 26% of the surgeons would treat their own appendicitis conservatively. There are distinct associations between the application of conservative therapy, satisfaction with it, and expectations about future development. The response rate was 19.9%.

CONCLUSION

The nonoperative antibiotic therapy of appendicitis is part of clinical practice in Germany. There are differences in preconditions as well as in the acceptance of this therapeutic option with a high proportion of general rejection.

摘要

背景

由于一些广为人知的研究,自2006年以来,非手术抗生素疗法被用于治疗单纯性急性阑尾炎。目前尚无法对其疗效和长期结果进行最终评估;然而,急性阑尾炎的非手术治疗实际上正受到更广泛的讨论并备受关注。这种疗法在日常临床护理中的应用程度仍不明确。

方法

向德国随机抽取的1400名普通/内脏外科专家发送了一份在线问卷。通过根据医院的地理来源和护理水平进行预选来确保代表性。

结果

14%的外科医生表示他们会系统地采用保守方法治疗阑尾炎。38.1%的医生在特殊情况下会这样做,而48.8%的医生拒绝这种疗法。对于系统使用该疗法,需要事先进行超声检查或计算机断层扫描。非手术治疗在大城市地区以及特级护理/大学医院中更为常用。患者对抗生素治疗的要求是保守治疗的一个重要因素。反对这种疗法的主要理由是“医学上的疑虑”。26%的外科医生会对自己的阑尾炎采用保守治疗。保守治疗的应用、对其的满意度以及对未来发展的期望之间存在明显的关联。回复率为19.9%。

结论

阑尾炎的非手术抗生素治疗是德国临床实践的一部分。在前提条件以及对这种治疗选择的接受程度方面存在差异,有很大比例的医生总体上拒绝这种疗法。

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