Rossi Gian Paolo, Bisogni Valeria, Bacca Alessandra Violet, Belfiore Anna, Cesari Maurizio, Concistrè Antonio, Del Pinto Rita, Fabris Bruno, Fallo Francesco, Fava Cristiano, Ferri Claudio, Giacchetti Gilberta, Grassi Guido, Letizia Claudio, Maccario Mauro, Mallamaci Francesca, Maiolino Giuseppe, Manfellotto Dario, Minuz Pietro, Monticone Silvia, Morganti Alberto, Muiesan Maria Lorenza, Mulatero Paolo, Negro Aurelio, Parati Gianfranco, Pengo Martino F, Petramala Luigi, Pizzolo Francesca, Rizzoni Damiano, Rossitto Giacomo, Veglio Franco, Seccia Teresa Maria
Clinica dell'Ipertensione Arteriosa, Department of Medicine - DIMED, University of Padua, Italy.
Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Int J Cardiol Hypertens. 2020 Apr 15;5:100029. doi: 10.1016/j.ijchy.2020.100029. eCollection 2020 Jun.
Considering the amount of novel knowledge generated in the last five years, a team of experienced hypertensionlogists was assembled to furnish updated clinical practice guidelines for the management of primary aldosteronism.
To identify the most relevant studies, the authors utilized a systematic literature review in international databases by applying the PICO strategy, and then they were required to make use of only those meeting predefined quality criteria. For studies of diagnostic tests, only those that fulfilled the Standards for Reporting of Diagnostic Accuracy recommendations were considered.
Each section was jointly prepared by at least two co-authors, who provided Class of Recommendation and Level of Evidence following the American Heart Association methodology. The guidelines were sponsored by the Italian Society of Arterial Hypertension and underwent two rounds of revision, eventually reexamined by an External Committee. They were presented and thoroughly discussed in two face-to-face meetings with all co-authors and then presented on occasion of the 36th Italian Society of Arterial Hypertension meeting in order to gather further feedbacks by all members. The text amended according to these feedbacks was subjected to a further peer review.
After this process, substantial updated information was generated, which could simplify the diagnosis of primary aldosteronism and assist practicing physicians in optimizing treatment and follow-up of patients with one of the most common curable causes of arterial hypertension.
鉴于过去五年产生的新知识数量，组建了一个由经验丰富的高血压专家组成的团队，以提供原发性醛固酮增多症管理的最新临床实践指南。
为了确定最相关的研究，作者通过应用PICO策略在国际数据库中进行了系统的文献综述，然后仅使用符合预定义质量标准的研究。对于诊断测试的研究，仅考虑那些符合诊断准确性报告标准建议的研究。
每个部分至少由两名共同作者共同编写，他们按照美国心脏协会的方法提供了推荐类别和证据级别。这些指南由意大利动脉高血压学会赞助，经过两轮修订，最终由一个外部委员会重新审查。它们在与所有共同作者的两次面对面会议上进行了展示和深入讨论，然后在第36届意大利动脉高血压学会会议上进行了展示，以便收集所有成员的进一步反馈。根据这些反馈修改后的文本进行了进一步的同行评审。
经过这个过程，产生了大量更新的信息，这可以简化原发性醛固酮增多症的诊断，并帮助执业医师优化对动脉高血压最常见可治愈病因之一的患者的治疗和随访。
