Department of Orthopaedic Surgery (E.M.F., N.A.L., J.N.K., and E.G.M.) and the Orthopedic and Arthritis Center for Outcomes Research (Y.C., K.R.A., and J.N.K.), Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Division of General Internal Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
J Bone Joint Surg Am. 2021 Mar 3;103(5):381-388. doi: 10.2106/JBJS.20.01193.
Traditionally defined "meniscal" and "mechanical" symptoms are thought to arise from meniscal tears. Yet meniscal tears and cartilage damage commonly coexist in symptomatic knees. To better characterize the primary driver of these symptoms, we investigated whether the presence of preoperative patient-reported knee symptoms (PRKS), including knee catching/locking, grinding/clicking/popping, and pain with pivoting, are associated with various intra-articular pathological conditions diagnosed at knee arthroscopy.
We collected prospective data from 565 consecutive patients who underwent knee arthroscopy from 2012 to 2019 and had PRKS collected via the Knee injury and Osteoarthritis Outcome Score (KOOS) questionnaire. The diagnosis of meniscal pathology and concomitant cartilage damage was confirmed and classified intraoperatively. We used multivariable regression models, adjusting for possible confounders, to examine the association of specific pathological conditions of the knee with the presence of preoperative PRKS.
Tricompartmental cartilage damage was strongly associated with significantly worse PRKS, with an increase of 0.33 point (95% confidence interval [CI] = 0.08 to 0.58; p = 0.01) on a 0 to 4-point scale. We did not observe an association between meniscal pathology and preoperative PRKS.
Contrary to current dogma, this study demonstrates that traditionally defined "meniscal" and "mechanical" knee symptoms are strongly associated with the burden and severity of underlying cartilage damage rather than with specific meniscal pathology.
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
传统定义的“半月板”和“机械性”症状被认为是由半月板撕裂引起的。然而,半月板撕裂和软骨损伤在有症状的膝关节中通常同时存在。为了更好地描述这些症状的主要驱动因素,我们研究了术前患者报告的膝关节症状(PRKS)的存在,包括膝关节卡顿/锁定、研磨/咔嗒/爆裂声以及旋转时疼痛,是否与膝关节镜检查诊断出的各种关节内病理状况有关。
我们收集了 2012 年至 2019 年间连续 565 例接受膝关节镜检查的患者的前瞻性数据,并通过膝关节损伤和骨关节炎结果评分(KOOS)问卷收集 PRKS。半月板病理和伴随软骨损伤的诊断在术中得到确认和分类。我们使用多变量回归模型,调整可能的混杂因素,检查膝关节特定病理状况与术前 PRKS 存在的相关性。
三间隙软骨损伤与 PRKS 显著恶化强烈相关,在 0 到 4 分的评分上增加了 0.33 分(95%置信区间 [CI] = 0.08 到 0.58;p = 0.01)。我们没有观察到半月板病理与术前 PRKS 之间的关联。
与当前的教条相反,本研究表明,传统定义的“半月板”和“机械性”膝关节症状与潜在软骨损伤的负担和严重程度密切相关,而与特定的半月板病理无关。
治疗学 IV 级。有关证据水平的完整描述,请参阅作者说明。