Paiement G, Wessinger S J, Waltman A C, Harris W H
Department of Orthopedic Research, Massachusetts General Hospital, Boston 02114.
Am J Surg. 1988 Mar;155(3):400-4. doi: 10.1016/s0002-9610(88)80099-0.
Nine hundred thirty-seven limbs in 537 patients over the age of 39 years who underwent total hip replacement were studied by roentgenographic phlebography, cuff-impedance phlebography, and iodine-125 fibrinogen scanning. Cuff-impedance phlebography had a sensitivity of only 12.3 percent for thigh thrombi. Fibrinogen scanning had a sensitivity of only 59.1 percent for calf thrombi and 13.7 percent for thigh thrombi. The combined use of the two methods resulted in only a 23.2 percent sensitivity for thigh thrombi and an overall sensitivity of 47.4 percent. We have concluded that in asymptomatic patients, in contrast with symptomatic patients, the combination of cuff-impedance phlebography and fibrinogen scanning is not an effective screening method.
对537例年龄超过39岁接受全髋关节置换术患者的937条肢体进行了X线静脉造影、袖带阻抗静脉造影和碘-125纤维蛋白原扫描研究。袖带阻抗静脉造影对大腿血栓的敏感性仅为12.3%。纤维蛋白原扫描对小腿血栓的敏感性仅为59.1%,对大腿血栓的敏感性为13.7%。两种方法联合使用对大腿血栓的敏感性仅为23.2%,总体敏感性为47.4%。我们得出结论,与有症状的患者相比,在无症状患者中,袖带阻抗静脉造影和纤维蛋白原扫描联合使用并非有效的筛查方法。