Clinic of Periodontology, Borås, Public Dental Service, Region Västra Götaland, Sweden.
Research and Development Unit, Borås, Sweden.
Clin Oral Implants Res. 2021 Apr;32(4):410-421. doi: 10.1111/clr.13711. Epub 2021 Feb 4.
To report a follow-up of patients following the surgical anti-infective treatment of peri-implantitis and to identify possible risk indicators for the progression of disease during supportive peri-implant therapy.
Following peri-implant surgery, 41 patients (213 implants) were enrolled in a supportive peri-implant therapy. At the 2-year follow-up, two groups of patients were identified, with or without residual peri-implant pockets (responding and non-responding group). Eighteen patients (85 implants) of the non-responding group were followed for further 8 years.
At the 2-year examination, 73 of the 117 treated implants (62.4%) presented healthy peri-implant condition, while 44 (37.6%) presented persisting peri-implantitis associated with substantial bone loss before treatment. The 10-year examination of the non-responding group revealed that 1) 84% of the implants that regained health following surgery remained healthy during the entire observation period; 2) 66% of the implants with residual pockets following surgery maintained stable peri-implant condition; and 3) 29% of all treated implants showed disease progression, and 11 of those were extracted. Presence of pockets at 3-4 sites of the implants was identified as risk indicator for progression of peri-implantitis.
The peri-implant health achieved following therapy was maintained for most of the implants during the follow-up. Residual pockets were a frequent finding at implants with substantial bone loss before treatment. Presence of pockets around the entire circumference of the implants resulted as a risk indicator for further disease progression. The probability of progression of peri-implant disease increased with increased observation time.
报告接受种植体周围炎抗感染治疗后患者的随访情况，并确定在支持性种植体治疗期间疾病进展的可能风险指标。
在种植体周围手术后，纳入 41 名患者（213 个种植体）进行支持性种植体治疗。在 2 年的随访中，确定了两组患者，一组有残留的种植体周袋（应答组和非应答组），另一组没有残留的种植体周袋。非应答组的 18 名患者（85 个种植体）进一步随访了 8 年。
在 2 年的检查中，117 个治疗种植体中有 73 个（62.4%）呈现健康的种植体周围状况，而 44 个（37.6%）呈现治疗前存在大量骨丧失的持续性种植体周围炎。非应答组的 10 年检查结果显示：1）手术后恢复健康的种植体中有 84%在整个观察期内保持健康；2）手术后仍有残留袋的种植体中有 66%保持稳定的种植体周围状况；3）所有治疗种植体中有 29%出现疾病进展，其中 11 个被拔除。种植体的 3-4 个部位存在袋状结构被确定为种植体周围炎进展的风险指标。
治疗后获得的种植体健康在随访期间的大多数种植体中得以维持。在治疗前存在大量骨丧失的种植体中，残留袋是一种常见的发现。种植体周围整个圆周存在袋状结构是疾病进一步进展的风险指标。种植体周围疾病进展的概率随着观察时间的增加而增加。
