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撤回:通过 SIRT1/PUMA/FOXO3a 去乙酰化作用耗尽 microRNA-183-3p 可改善急性肾损伤后的肾小管间质纤维化。

RETRACTED: Depleting microRNA-183-3p improves renal tubulointerstitial fibrosis after acute kidney injury via SIRT1/PUMA/FOXO3a deacetylation.

机构信息

Emergency and Critical Care Center, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, Hubei, China.

Department of Nephrology, Renmin Hospital, Hubei University of Medicine, Shiyan 442000, Hubei, China.

出版信息

Life Sci. 2021 Mar 15;269:119017. doi: 10.1016/j.lfs.2021.119017. Epub 2021 Jan 12.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. Concern was raised about the reliability of the Western blot results in Figs. 2E, and 3C, which appear to have the same eyebrow shaped phenotype as many other publications tabulated here (https://docs.google.com/spreadsheets/d/149EjFXVxpwkBXYJOnOHb6RhAqT4a2llhj9LM60MBffM/edit#gid=0). The journal requested the corresponding author comment on these concerns and provide the raw data. However the authors were not able to satisfactorily fulfil this request and therefore the Editor-in-Chief decided to retract the article.

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