Schapira D, Ludatscher R, Nahir M, Lorber M, Scharf Y
Department of Rheumatology, Rambam Medical Center, Haifa, Israel.
Ann Rheum Dis. 1988 Jan;47(1):80-3. doi: 10.1136/ard.47.1.80.
Severe myalgia is an uncommon feature of familial Mediterranean fever (FMF). A patient is presented in whom acute myalgia and high fever were the sole clinical findings during an FMF attack. The ultrastructural picture of the muscle tissue during the acute stage was characterised by a large deposition of collagen fibrils. The myalgia subsided during colchicine treatment. The clinical and ultrastructural features of myalgia in FMF are discussed in the light of the relevant literature.
严重肌痛是家族性地中海热（FMF）的一种罕见特征。本文报告了一名患者，在FMF发作期间，急性肌痛和高热是唯一的临床症状。急性期肌肉组织的超微结构表现为胶原纤维大量沉积。秋水仙碱治疗期间肌痛消退。结合相关文献对FMF中肌痛的临床和超微结构特征进行了讨论。
