Meere M, Borrell J
Department of Psychobiology, Cajal Institute, CSIC, Velázquez, Madrid, Spain.
Behav Neural Biol. 1988 Jan;49(1):1-11. doi: 10.1016/s0163-1047(88)91162-4.
Hormones and peptides involved in the response of an organism to stress play a modulating role in learning and memory processes. We studied whether psychoneurogenic stressors such as sound stimulation or novelty influence retention of an inhibitory avoidance response. An impairing effect on retention was observed when these stressors were applied shortly after the acquisition trial, but not after a 3-h delay. However, sound stimulation and novelty applied shortly before the retention test may facilitate retention behavior. It is suggested that the effect of psychoneurogenic stressors on retention behavior may be linked to influences on consolidation and retrieval processes mediated through the neurohumoral response of the organism to stress.
参与生物体应激反应的激素和肽在学习和记忆过程中起调节作用。我们研究了诸如声音刺激或新奇事物等心理神经源性应激源是否会影响抑制性回避反应的保持。当在习得试验后不久施加这些应激源时，观察到对保持有损害作用，但在延迟3小时后则没有。然而，在保持测试前不久施加声音刺激和新奇事物可能会促进保持行为。有人提出，心理神经源性应激源对保持行为的影响可能与通过生物体对应激的神经体液反应介导的对巩固和检索过程的影响有关。
