Department of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA; Integrative Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA.
Department of Physical Therapy, Ithaca College, Ithaca, NY, USA.
Prog Cardiovasc Dis. 2022 Jul-Aug;73:61-66. doi: 10.1016/j.pcad.2020.12.010. Epub 2021 Jan 13.
Sedentary behavior (SB) and physical activity (PA) are important risk factors of cardiovascular disease morbidity and mortality. In addition to increasing the amount of moderate-to-vigorous PA (MVPA), the current PA guidelines recommend that adults should reduce SB, or any waking activity performed while sitting, reclining, or lying, with low energy expenditure. While mounting evidence has emphasized the benefits of increasing MVPA, little has focused on the effect of SB on health. Therefore, this review discusses the pathophysiological effects of SB and the potential physiological benefits of reducing/breaking up SB at the levels below the current guidelines for PA. Such knowledge is important, given that the majority of the United States population performs insufficient or no MVPA and is at high risk of being negatively impacted by SB. Interventions targeting sedentary time, such as breaking up SB by standing and moving, may be safe, feasible, and applicable to execute daily for a wide range of the population. This review also discusses the importance of monitoring SB in the era of the coronavirus disease 2019 (COVID-19) pandemic and the clinical implications of sitting less and moving more.
久坐行为（SB）和身体活动（PA）是心血管疾病发病率和死亡率的重要危险因素。除了增加中等至剧烈强度身体活动（MVPA）的量外，目前的 PA 指南还建议成年人减少 SB，即任何低能量消耗的坐着、斜倚或躺着时进行的清醒活动。虽然越来越多的证据强调了增加 MVPA 的益处，但很少关注 SB 对健康的影响。因此，本综述讨论了 SB 的病理生理影响，以及在低于当前 PA 指南的水平下减少/打断 SB 的潜在生理益处。鉴于大多数美国人口的 MVPA 不足或没有，并且有很高的风险受到 SB 的负面影响，因此这种知识非常重要。针对久坐时间的干预措施，例如通过站立和移动来打断 SB，可能是安全、可行的，并且适用于广泛人群日常执行。本综述还讨论了在 2019 年冠状病毒病（COVID-19）大流行时代监测 SB 的重要性，以及减少久坐和增加活动的临床意义。
