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描述一例 16 孕周的晚期流产病例,与 SARS-CoV-2 感染相关。

Description of a late miscarriage case at 16 Weeks of Gestation associated with a SARS-CoV-2 infection.

机构信息

Department of Obstetrics and Gynecology, FHU PREMA, Trousseau Hospital, Paris, France; Sorbonne University, Paris, France.

Department of Obstetrics and Gynecology, FHU PREMA, Trousseau Hospital, Paris, France.

出版信息

J Gynecol Obstet Hum Reprod. 2021 Mar;50(3):102064. doi: 10.1016/j.jogoh.2021.102064. Epub 2021 Jan 13.

DOI:10.1016/j.jogoh.2021.102064
PMID:33453449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7805395/
Abstract

BACKGROUND

Data about obstetric complications of maternal infection by SARS-CoV-2 remain sparse.

CASE

A 40-year-old pregnant woman, gravida 3 para 1 with no previous obstetric complications, presented a late miscarriage at 16 weeks of gestation on day 9 of COVID-19 disease. The results of her nasopharyngeal swab for SARS-CoV-2, tested the same day, were negative, but the placenta was infected by SARS-CoV-2 and serology was positive 11 days later. No other obstetric or infectious cause was found to explain this outcome.

CONCLUSION

This case strongly suggests that SARS-CoV-2 may lead to a late miscarriage.

摘要

背景

关于 SARS-CoV-2 感染产妇的产科并发症的数据仍然很少。

病例

一位 40 岁的孕妇,第 3 次妊娠,第 1 次分娩,无既往产科并发症,在 COVID-19 疾病第 9 天出现 16 周妊娠的晚期流产。同一天检测到她的鼻咽拭子 SARS-CoV-2 结果为阴性,但胎盘被 SARS-CoV-2 感染,11 天后血清学呈阳性。没有发现其他产科或感染原因可以解释这种结果。

结论

本病例强烈提示 SARS-CoV-2 可能导致晚期流产。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0dbc/7805395/52654910a7a6/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0dbc/7805395/b724b1682952/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0dbc/7805395/52654910a7a6/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0dbc/7805395/b724b1682952/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0dbc/7805395/52654910a7a6/gr2_lrg.jpg

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