van Twisk R, Gielen M J, Pavlov P W, Robinson P H
Nijmegen University Hospital St Radboud, St Maartens Clinic-Nijmegen, The Netherlands.
Br J Plast Surg. 1988 Jan;41(1):37-40. doi: 10.1016/0007-1226(88)90142-7.
The use of additional epidural sympathetic block during and after microvascular surgery in the lower extremities to prevent vasospasm is generally agreed on. However, a significant fall in the perfusion rate of the transplants was seen after application of bupivacaine (Marcain) via the epidural catheter. This effect has, to our knowledge, not been described before and is probably caused by the sympathectomy effect of this type of analgesia.
在下肢微血管手术期间及术后使用额外的硬膜外交感神经阻滞来预防血管痉挛已得到普遍认可。然而,通过硬膜外导管应用布比卡因(耐乐品)后,观察到移植物的灌注率显著下降。据我们所知,这种效应此前尚未被描述过,可能是由这类镇痛的交感神经切除术效应所致。