羊膜带断裂综合征。先天性肢体环形缩窄的发病机制；对胎鼠的一项实验研究。

The amniotic band disruption complex. The pathogenesis of congenital limb ring-constrictions; an experimental study in the foetal rat.

作者信息

Rowsell A R

机构信息

Department of Plastic Surgery, Radcliffe Infirmary, Oxford.

出版信息

Br J Plast Surg. 1988 Jan;41(1):45-51. doi: 10.1016/0007-1226(88)90144-0.

DOI:10.1016/0007-1226(88)90144-0

PMID:3345407

Abstract

This paper reports the findings of an experimental foetal rat study which has shown that it is possible to produce mild, moderate and severe limb ring-constrictions by simulating the ligature effect of amniotic bands. Of the 40 experimental foetuses, 36 (90%) survived the in utero surgery and are included in the present study. Of these 36 foetuses, limb constriction rings were produced in 35 (97%), and an in utero limb amputation in one (3%).

摘要

本文报告了一项对胎鼠的实验研究结果，该研究表明，通过模拟羊膜带的结扎效应，可以产生轻度、中度和重度肢体环状缩窄。在40只实验胎鼠中，36只（90%）在子宫内手术中存活下来，并纳入本研究。在这36只胎鼠中，35只（97%）产生了肢体缩窄环，1只（3%）在子宫内发生了肢体截肢。