Shuaib A, Martin J M, Mitchell L B, Brownell A K
Department of Clinical Neurosciences, Faculty of Medicine, University of Calgary, Alberta, Canada.
Can J Neurol Sci. 1988 Feb;15(1):10-4. doi: 10.1017/s0317167100027098.
Four patients with Multicore Myopathy, a rare morphologically distinct myopathy, are described. Although previously considered to be a non-progressive or only slowly progressive myopathy, progression to significant disability was seen in three of our cases. The association of cardiac disease with Multicore Myopathy has not been previously emphasised. All four patients in this study had a cardiomyopathy, and heart disease was the cause of death in two of the patients. Multicore Myopathy is not always a benign entity. Cardiac involvement, when present, adversely affects prognosis.
本文描述了4例多核肌病患者，这是一种罕见的形态学上独特的肌病。尽管此前认为它是非进行性或仅缓慢进展性肌病，但我们的3例患者出现了进展至严重残疾的情况。此前未强调过心脏病与多核肌病的关联。本研究中的所有4例患者均患有心肌病，其中2例患者死于心脏病。多核肌病并不总是一种良性疾病。一旦出现心脏受累，会对预后产生不利影响。
